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XL-3 Cold Medicine (acetaminophen / chlorpheniramine / phenylephrine) Drug Interactions

A total of 980 drugs are known to interact with XL-3 Cold Medicine (acetaminophen / chlorpheniramine / phenylephrine).

  • 250 major drug interactions
  • 693 moderate drug interactions
  • 37 minor drug interactions

Show all medications in the database that may interact with XL-3 Cold Medicine (acetaminophen / chlorpheniramine / phenylephrine).

Check for interactions with XL-3 Cold Medicine (acetaminophen / chlorpheniramine / phenylephrine)

Type in a drug name and select a drug from the list.

Common medications checked in combination with XL-3 Cold Medicine (acetaminophen / chlorpheniramine / phenylephrine)

  • Adderall (amphetamine / dextroamphetamine)
  • albuterol (Ventolin, ProAir HFA, Ventolin HFA, Proventil, Proventil HFA, ProAir RespiClick, Respirol, AccuNeb, Vospire ER, Airet, Volmax, ProAir Digihaler)
  • Alcohol (contained in alcoholic beverages) (ethanol)
  • Allegra (fexofenadine)
  • atorvastatin (Lipitor)
  • Bayer Aspirin (aspirin)
  • benazepril (Lotensin)
  • cannabis
  • Cheratussin AC (codeine / guaifenesin)
  • Cold & Cough (chlorpheniramine / dextromethorphan)
  • diphenhydramine (Benadryl, Banophen, Benadryl Allergy, ZzzQuil, Unisom SleepGels, Dicopanol, Sleep, Diphenhist, Sominex, Diphen, Diphenadryl, Benadryl Children's Allergy, Allermax, Diphenydramine Quick Melt, Nytol, Diphedryl, Hydramine, Diphendryl, Pharbedryl, Buckley's Bedtime, Hyrexin, Hydramine Cough Syrup, Bydramine, Diphen Cough, DPH, Allergia-C, Q-Dryl, Sleep Tabs, Quenalin, Sleep-ettes D, Q-Dryl A/F, Dytan, Vanamine PD, Sleepwell 2-nite, Snooze Fast, Sominex Maximum Strength Caplet, Unisom SleepMinis, Unisom Liquid, Triaminic Thin Strips Allergy, ConRx Allergy, 40 Winks, Diphen AF, Aler-Dryl, Benahist-10, Benahist-50, Benoject-50, Calm-Aid, Genahist, Alka-Seltzer Plus Allergy, Aller-G-Time, Sleep Tab II, Sleep-Eze-3, Somnicaps, Nytol QuickCaps, Total Allergy, Trux-adryl, Valu-Dryl, Diphenyl, Altaryl, Triaminic Thin Strips Cough & Runny Nose, Beldin, Belix, Vicks QlearQuil Nighttime Allergy Relief, Siladryl, Siladryl DAS, Siladyl SA, Silphen Cough, Sleep-ettes, Tusstat, Diphenylin, Hydramine Compound, Pardryl, Nervine, Nu-Med, Nytol Caplet, Compoz Nighttime Sleep Aid, Sleepinal, Help I Can't Sleep, Twilite, Banaril, Aler-Tab, Siladryl Allergy, Theraflu Thin Strips Multi Symptom, Uni-Tann, Diphenmax, Nightime Sleepaid, Ben-Tann, Histaprin, Z-Sleep, Tranquil Nighttime Sleep Aid, Unisom SleepMelts, PediaCare Children's Allergy, Truxadryl, Simply Sleep, Complete Allergy Relief, Dytuss, Dormin, Miles Nervine, Scot-Tussin Allergy)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Proprinal, Motrin IB, Children's Motrin, IBU-200, Advil Migraine, Ibu-8, Motrin Childrens, Nuprin, Motrin Migraine Pain, Ibuprofen PMR, NeoProfen, Caldolor, Advil Children's, Addaprin, Motrin Infant Drops, Advil Infant's Concentrated Drops, Rufen, Genpril, A-G Profen, Ibu-Tab, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, Childrens Ibuprofen Berry, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • Lipitor (atorvastatin)
  • meclizine (Antivert, Dramamine Less Drowsy, Bonine, Meclicot, Travel Sickness, Dramamine II, Dramamine All Day Less Drowsy, Travel-Ease, Sea-Calm, Antrizine, Medivert, D-Vert, Driminate II, Ru-Vert-M, Meni-D, Help I'm Nauseous, Motion-Time, Verticalm)
  • metformin (Glucophage, Glucophage XR, Glumetza, Riomet, Fortamet)
  • Metoprolol Tartrate (metoprolol)
  • OxyContin (oxycodone)
  • paroxetine (Paxil, Paxil CR, Brisdelle, Pexeva)
  • tamsulosin (Flomax)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Larapam SR, Tramedo, Ryzolt, GenRx Tramadol, ConZip, Zydol, Tramal SR, Tramahexal, Zamadol, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • Wellbutrin (bupropion)

XL-3 Cold Medicine (acetaminophen / chlorpheniramine / phenylephrine) alcohol/food interactions

There is 1 alcohol/food interaction with XL-3 Cold Medicine (acetaminophen / chlorpheniramine / phenylephrine)

XL-3 Cold Medicine (acetaminophen / chlorpheniramine / phenylephrine) disease interactions

There are 11 disease interactions with XL-3 Cold Medicine (acetaminophen / chlorpheniramine / phenylephrine) which include:

More about XL-3 Cold Medicine (acetaminophen / chlorpheniramine / phenylephrine)

Related treatment guides

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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