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Macrolides

What are Macrolides

Macrolides are a class of antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), a type of soil-borne bacteria.

Macrolides inhibit protein synthesis in bacteria by reversibly binding to the P site of the 50S unit of the ribosome. Macrolides mainly affect gram-positive cocci and intracellular pathogens such as mycoplasma, chlamydia, and legionella. Erythromycin was the first macrolide discovered; other macrolides include azithromycin, clarithromycin, and roxithromycin.

Their action is primarily bacteriostatic but may be bactericidal at high concentrations, or depending on the type of microorganism.

List of Macrolides:

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Drug NameView by: Brand | Generic Reviews Avg. Ratings
fidaxomicin systemic (Pro, More...)
6 reviews
   
7.3
azithromycin systemic (Pro, More...)
782 reviews
   
7.2
erythromycin systemic (Pro, More...)
27 reviews
   
6.5
clarithromycin systemic (Pro, More...)
433 reviews
   
5.7
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