Simethicone Dosage

Medically reviewed by Drugs.com. Last updated on Apr 9, 2024.

Applies to the following strengths: 125 mg; 60 mg; 95 mg; 40 mg/0.6 mL; 180 mg; 80 mg; 62.5 mg; 166 mg; 50 mg/5 mL; 40 mg; 150 mg; 250 mg; 20 mg/0.3 mL; 62.5 mg/5 mL

Usual Adult Dose for Dyspepsia

Chewable Tablets: 80 to 160 mg orally after meals and at bedtime as needed

Extra Strength (125 mg) Capsules: 125 to 250 mg orally after meals and at bedtime as needed

Ultra Strength (180 mg) Capsules: 180 to 360 mg orally once after a meal or at bedtime as needed

Maximum Strength (250 mg) Capsules: 250 to 500 mg orally once after a meal

Tablets: 125 mg orally 3 times a day as needed after meals or at bedtime

Maximum dose: 500 mg/day

Comments:

Patients should not exceed the maximum daily dose unless otherwise directed.
Doses taken at bedtime pay provide overnight symptom relief.

Use: Relief of gas bloating, fullness, pressure, or a stuffed feeling

Usual Adult Dose for Flatulence

Patients should not exceed the maximum daily dose unless otherwise directed.
Doses taken at bedtime pay provide overnight symptom relief.

Use: Relief of gas bloating, fullness, pressure, or a stuffed feeling

Usual Pediatric Dose for Flatulence

Age-based dosing:

Infants less than 2 years: 20 mg orally after meals and at bedtime as needed
Maximum dose: 240 mg/day
Children greater than 2 years: 40 mg orally after meals and at bedtime as needed
Maximum dose: 480 mg/day

Weight-based dosing:

Under 10.9 kg: 20 mg orally after meals and at bedtime as needed
Maximum dose: 240 mg/day
Over 10.9 kg: 40 mg orally after meals and at bedtime as needed
Maximum dose: 480 mg/day

Comments:

Weight-based dosing should be used when possible.
Caregivers should be instructed to use the enclosed syringe; other dosing devices should not be used to dose this drug.
Doses may be administered by dispensing into the child's mouth OR by mixing with 30 mL cool water, infant formula, or other liquids.

Use: Relief of infant gas frequently caused by air swallowing or certain formulas or foods

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

Hypersensitivity to the active component or any of the ingredients

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Oral drops/emulsions/solutions/suspensions: Shake prior to use.

Storage requirements:

Capsules: Protect from heat, light, and moisture
Chewable tablets and tablets: Protect from moisture
Oral drops/emulsions: Do not freeze
Oral suspensions: Once opened, discard after 28 days.

Reconstitution/preparation techniques:

Oral drops/emulsions: May be mixed with 1 oz of cool water, infant formula, or suitable liquids immediately prior to administration

Patient advice:

Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
Patients should be instructed to avoid using products if the tamper evident feature(s) are torn, broken, and/or missing.