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Simethicone Dosage

Medically reviewed by Drugs.com. Last updated on Aug 20, 2018.

Applies to the following strengths: 125 mg; 60 mg; 95 mg; 40 mg/0.6 mL; 180 mg; 80 mg; 62.5 mg; 166 mg; 50 mg/5 mL; 40 mg; 150 mg; 250 mg; 62.5 mg/5 mL

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Dyspepsia

Chewable Tablets: 80 to 160 mg orally after meals and at bedtime as needed

Extra Strength (125 mg) Capsules: 125 to 250 mg orally after meals and at bedtime as needed

Ultra Strength (180 mg) Capsules: 180 to 360 mg orally once after a meal or at bedtime as needed

Maximum Strength (250 mg) Capsules: 250 to 500 mg orally once after a meal

Tablets: 125 mg orally 3 times a day as needed after meals or at bedtime

Maximum dose: 500 mg/day

Comments:
-Patients should not exceed the maximum daily dose unless otherwise directed.
-Doses taken at bedtime pay provide overnight symptom relief.

Use: Relief of gas bloating, fullness, pressure, or a stuffed feeling

Usual Adult Dose for Flatulence

Chewable Tablets: 80 to 160 mg orally after meals and at bedtime as needed

Extra Strength (125 mg) Capsules: 125 to 250 mg orally after meals and at bedtime as needed

Ultra Strength (180 mg) Capsules: 180 to 360 mg orally once after a meal or at bedtime as needed

Maximum Strength (250 mg) Capsules: 250 to 500 mg orally once after a meal

Tablets: 125 mg orally 3 times a day as needed after meals or at bedtime

Maximum dose: 500 mg/day

Comments:
-Patients should not exceed the maximum daily dose unless otherwise directed.
-Doses taken at bedtime pay provide overnight symptom relief.

Use: Relief of gas bloating, fullness, pressure, or a stuffed feeling

Usual Pediatric Dose for Flatulence

Age-based dosing:
-Infants less than 2 years: 20 mg orally after meals and at bedtime as needed
---Maximum dose: 240 mg/day
-Children greater than 2 years: 40 mg orally after meals and at bedtime as needed
---Maximum dose: 480 mg/day

Weight-based dosing:
-Under 10.9 kg: 20 mg orally after meals and at bedtime as needed
---Maximum dose: 240 mg/day
-Over 10.9 kg: 40 mg orally after meals and at bedtime as needed
---Maximum dose: 480 mg/day

Comments:
-Weight-based dosing should be used when possible.
-Caregivers should be instructed to use the enclosed syringe; other dosing devices should not be used to dose this drug.
-Doses may be administered by dispensing into the child's mouth OR by mixing with 30 mL cool water, infant formula, or other liquids.

Use: Relief of infant gas frequently caused by air swallowing or certain formulas or foods

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
-Hypersensitivity to the active component or any of the ingredients

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Oral drops/emulsions/solutions/suspensions: Shake prior to use.

Storage requirements:
-Capsules: Protect from heat, light, and moisture
-Chewable tablets and tablets: Protect from moisture
-Oral drops/emulsions: Do not freeze
-Oral suspensions: Once opened, discard after 28 days.

Reconstitution/preparation techniques:
-Oral drops/emulsions: May be mixed with 1 oz of cool water, infant formula, or suitable liquids immediately prior to administration

Patient advice:
-Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
-Patients should be instructed to avoid using products if the tamper evident feature(s) are torn, broken, and/or missing.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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