Simethicone Dosage

Medically reviewed by Drugs.com. Last updated on Jul 28, 2023.

Usual Adult Dose for Dyspepsia

Chewable Tablets: 80 to 160 mg orally after meals and at bedtime as needed

Extra Strength (125 mg) Capsules: 125 to 250 mg orally after meals and at bedtime as needed

Ultra Strength (180 mg) Capsules: 180 to 360 mg orally once after a meal or at bedtime as needed

Maximum Strength (250 mg) Capsules: 250 to 500 mg orally once after a meal

Tablets: 125 mg orally 3 times a day as needed after meals or at bedtime

Maximum dose: 500 mg/day

Comments:

• Patients should not exceed the maximum daily dose unless otherwise directed.
• Doses taken at bedtime pay provide overnight symptom relief.

Use: Relief of gas bloating, fullness, pressure, or a stuffed feeling

Usual Adult Dose for Flatulence

Chewable Tablets: 80 to 160 mg orally after meals and at bedtime as needed

Extra Strength (125 mg) Capsules: 125 to 250 mg orally after meals and at bedtime as needed

Ultra Strength (180 mg) Capsules: 180 to 360 mg orally once after a meal or at bedtime as needed

Maximum Strength (250 mg) Capsules: 250 to 500 mg orally once after a meal

Tablets: 125 mg orally 3 times a day as needed after meals or at bedtime

Maximum dose: 500 mg/day

Comments:

• Patients should not exceed the maximum daily dose unless otherwise directed.
• Doses taken at bedtime pay provide overnight symptom relief.

Use: Relief of gas bloating, fullness, pressure, or a stuffed feeling

Usual Pediatric Dose for Flatulence

Age-based dosing:

• Infants less than 2 years: 20 mg orally after meals and at bedtime as needed
• Maximum dose: 240 mg/day
• Children greater than 2 years: 40 mg orally after meals and at bedtime as needed
• Maximum dose: 480 mg/day

Weight-based dosing:

• Under 10.9 kg: 20 mg orally after meals and at bedtime as needed
• Maximum dose: 240 mg/day
• Over 10.9 kg: 40 mg orally after meals and at bedtime as needed
• Maximum dose: 480 mg/day

Comments:

• Weight-based dosing should be used when possible.
• Caregivers should be instructed to use the enclosed syringe; other dosing devices should not be used to dose this drug.
• Doses may be administered by dispensing into the child's mouth OR by mixing with 30 mL cool water, infant formula, or other liquids.

Use: Relief of infant gas frequently caused by air swallowing or certain formulas or foods

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Hypersensitivity to the active component or any of the ingredients

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Oral drops/emulsions/solutions/suspensions: Shake prior to use.

Storage requirements:

• Capsules: Protect from heat, light, and moisture
• Chewable tablets and tablets: Protect from moisture
• Oral drops/emulsions: Do not freeze
• Oral suspensions: Once opened, discard after 28 days.

Reconstitution/preparation techniques:

• Oral drops/emulsions: May be mixed with 1 oz of cool water, infant formula, or suitable liquids immediately prior to administration

Patient advice:

• Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
• Patients should be instructed to avoid using products if the tamper evident feature(s) are torn, broken, and/or missing.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer