Medically reviewed by Drugs.com. Last updated on Oct 12, 2021.
2.1 Recommended Dosage
The recommended dosage of QULIPTA is 10 mg, 30 mg, or 60 mg taken orally once daily with or without food.
2.2 Dosage Modifications
Dosing modifications for concomitant use of specific drugs and for patients with renal impairment are provided in Table 1.
Table 1: Dosage Modifications for Drug Interactions and for Specific Populations
|Dosage Modifications||Recommended Once Daily Dosage|
|Concomitant Drug [see Drug Interactions (7)]|
|Strong CYP3A4 Inhibitors (7.1)||10 mg|
|Strong and Moderate CYP3A4 Inducers (7.2)||30 mg or 60 mg|
|OATP Inhibitors (7.3)||10 mg or 30 mg|
|Renal Impairment [see Use in Specific Populations (8)]|
| Severe Renal Impairment and End-Stage Renal
Disease (CLcr <30 mL/min) (8.6)
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