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Pronestyl Dosage

Generic name: procainamide hydrochloride
Dosage form: Tablets USP and Capsules USP
Drug class: Group I antiarrhythmics

Medically reviewed by Last updated on May 1, 2023.

The oral dose and interval of administration should be adjusted for the individual patient, based on clinical assessment of the degree of underlying myocardial diseased, the patient’s age, and renal function.

As a general guide, for younger adult patients with normal renal function, an initial total daily oral dose of up to 50 mg/kg of body weight of PRONESTYL Capsules or Tablets may be used, given in divided doses, every three hours, to maintain therapeutic blood levels. For older patients, especially those over 50 years of age, or for patients with renal, hepatic, or cardiac insufficiency, lesser amounts or longer intervals may produce adequate blood levels, and decrease the probability of occurrence of dose-related adverse reactions. The total daily dose should be administered in divided doses at three, four, or six hour intervals and adjusted according to the patient’s response.

To provide approximately 50 mg per kg of body weight per day*
Patients weighing
lb kg
*Initial dosage schedule guide only, to be adjusted for each patient individually, based on age, cardiorenal function, blood level (if available), and clinical response.
88-110 40-50 250 mg q3h to 500 mg q6h
132-154 60-70 375 mg q3h to 750 mg q6h
176-198 80-90 500 mg q3 hr to 1 g q6h
>220 >100 625 mg q3h to 1.25 g q6h

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.