Ofloxacin Ophthalmic Dosage

Medically reviewed by Drugs.com. Last updated on May 1, 2025.

Usual Adult Dose for Bacterial Conjunctivitis

Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 2 to 4 hours.
Days 3 through 7: Instill 1 to 2 drops in the affected eye(s) 4 times a day.

Use: For the treatment of bacterial conjunctivitis due to susceptible strains of Staphylococcus aureus, S epidermidis, Streptococcus pneumoniae, Enterobacter cloacae, Haemophilus influenzae, Proteus mirabilis, Pseudomonas aeruginosa

Usual Adult Dose for Corneal Ulcers

Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 30 minutes while awake and about 4 and 6 hours after retiring.
Days 3 through 7 to 9: Instill 1 to 2 drops in the affected eye(s) every hour while awake.
Days 7 to 9 through treatment completion: Instill 1 to 2 drops in the affected eye(s) 4 times a day.

Use: For the treatment of bacterial corneal ulcers due to susceptible strains of S aureus, S epidermidis, S pneumoniae, P aeruginosa, Serratia marcescens, Propionibacterium acnes

Usual Pediatric Dose for Bacterial Conjunctivitis

1 year or older:

• Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 2 to 4 hours.
• Days 3 through 7: Instill 1 to 2 drops in the affected eye(s) 4 times a day.

Use: For the treatment of bacterial conjunctivitis due to susceptible strains of S aureus, S epidermidis, S pneumoniae, E cloacae, H influenzae, P mirabilis, P aeruginosa

Usual Pediatric Dose for Corneal Ulcers

1 year or older:

• Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 30 minutes while awake and about 4 and 6 hours after retiring.
• Days 3 through 7 to 9: Instill 1 to 2 drops in the affected eye(s) every hour while awake.
• Days 7 to 9 through treatment completion: Instill 1 to 2 drops in the affected eye(s) 4 times a day.

Use: For the treatment of bacterial corneal ulcers due to susceptible strains of S aureus, S epidermidis, S pneumoniae, P aeruginosa, S marcescens, P acnes

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 1 year.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• For topical ophthalmic use only (not for injection)
• Do not inject subconjunctivally; do not introduce directly into the anterior chamber of the eye.
• Consult the manufacturer product information for instillation instructions.
• If other topical ophthalmic agents are used, wait at least 10 minutes between instillations.

Patient advice:

• Do not wear contact lenses during therapy.
• Wash hands thoroughly before using this drug.
• Avoid contaminating the applicator tip with material from the eye, fingers, or any other source.
• Stop this drug and contact physician at first sign of rash or allergic reaction.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer