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Guaifenesin / Pseudoephedrine Dosage

Medically reviewed by Drugs.com. Last updated on Oct 31, 2018.

Applies to the following strengths: 400 mg-60 mg; 600 mg-120 mg; 200 mg-30 mg; 100 mg-30 mg/5 mL; 50 mg-15 mg/5 mL; 50 mg-15 mg; 400 mg-120 mg; 600 mg-60 mg; 250 mg-120 mg; 300 mg-60 mg; 1200 mg-120 mg; 125 mg-60 mg; 200 mg-60 mg; 500 mg-120 mg; 100 mg-60 mg; 250 mg-30 mg; 800 mg-80 mg; 600 mg-45 mg; 595 mg-48 mg; 200 mg-45 mg/5 mL; 600 mg-90 mg; 795 mg-85 mg; 200 mg-40 mg/5 mL; 1200 mg-60 mg; 1200 mg-90 mg; 500 mg-60 mg; 800 mg-90 mg; 1200 mg-50 mg; 800 mg-120 mg; 250 mg-90 mg; 150 mg-30 mg; 800 mg-60 mg; 380 mg-60 mg; 650 mg-90 mg; 400 mg-45 mg; 650 mg-45 mg; 50 mg-7.5 mg/mL; 400 mg-90 mg; 400 mg-40 mg; 400 mg-30 mg; 400 mg-20 mg; 550 mg-60 mg; 700 mg-80 mg; 580 mg-60 mg; 780 mg-80 mg; 525 mg-50 mg; 525 mg-120 mg; 800 mg-45 mg; 1200 mg-75 mg; 1000 mg-60 mg; 375 mg-60 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cough and Nasal Congestion

Immediate release tablets: 1 tablet orally every 4 hours
Maximum dose: 4 tablets per 24 hours


Extended release (600 mg/ 60 mg) tablets: 2 tablets orally every 12 hours
Maximum dose: 4 tablets per 24 hours


Maximum strength (1200 mg/ 120 mg) extended release tablets: 1 tablet orally every 12 hours
Maximum dose: 2 tablets per 24 hours

Usual Pediatric Dose for Cough and Nasal Congestion

Immediate release tablets:
12 years and older: 1 tablet orally every 4 hours
Maximum dose: 4 tablets per 24 hours

6 to 12 years: One half tablet orally every 4 hours
Maximum dose: 2 tablets per 24 hours


Extended release (600 mg/ 60 mg) tablets:
12 years and older: 2 tablets orally every 12 hours
Maximum dose: 4 tablets per 24 hours


Maximum strength (1200 mg/ 120 mg) extended release tablets:
12 years and older: 1 tablet orally every 12 hours
Maximum dose: 2 tablets per 24 hours


25 mg/ 7.5 mg/ mL liquid:
2 to under 6 years (11 to 21 kg): 2 mL every 4 to 6 hours
Maximum dose: 4 doses per 24 hours

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
-Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI

Safety and efficacy have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Do not crush, break, or chew extended or sustained release tablets.
-Extended release tablets may be taken without regard for timing of meals

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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