Guaifenesin/pseudoephedrine Interactions
There are 220 drugs known to interact with guaifenesin/pseudoephedrine, along with 6 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 21 are major, 193 are moderate, and 6 are minor.
- View all 220 medications that may interact with guaifenesin/pseudoephedrine
- View guaifenesin/pseudoephedrine alcohol/food interactions (1)
- View guaifenesin/pseudoephedrine disease interactions (6)
Most frequently checked interactions
View interaction reports for guaifenesin / pseudoephedrine and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- 5-HTP (5-hydroxytryptophan)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- Celebrex (celecoxib)
- Claritin (loratadine)
- Claritin (loratadine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Flonase (fluticasone nasal)
- Mucinex (guaifenesin)
- Mucinex (guaifenesin)
- Mucinex DM (dextromethorphan / guaifenesin)
- Mucinex DM (dextromethorphan / guaifenesin)
- Norvasc (amlodipine)
- Norvasc (amlodipine)
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
- Valerian Root (valerian)
- Valerian Root (valerian)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Guaifenesin/pseudoephedrine alcohol/food interactions
There is 1 alcohol/food interaction with guaifenesin / pseudoephedrine.
Guaifenesin/pseudoephedrine disease interactions
There are 6 disease interactions with guaifenesin / pseudoephedrine which include:
Report options
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- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Promethazine VC with Codeine
Promethazine VC with Codeine is used for cough and nasal congestion
Mucinex D
Mucinex D (guaifenesin and pseudoephedrine) is used to treat nasal and sinus congestion, and to ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
