Emtriva Dosage

Generic name: EMTRICITABINE 200mg
Dosage form: capsule, oral solution
Drug class: Nucleoside reverse transcriptase inhibitors (NRTIs)

Medically reviewed by Drugs.com. Last updated on Jun 19, 2024.

Testing Prior to Initiation of Treatment with EMTRIVA

Prior to or when initiating EMTRIVA, test patients for hepatitis B virus infection.

Recommended Dosage

EMTRIVA is taken by mouth once daily and may be taken without regard to food.

Recommended Dosage in Adult Patients (18 years of age and older)

EMTRIVA capsules: One 200 mg capsule administered once daily orally.

EMTRIVA oral solution: 240 mg (24 mL) administered once daily orally.

Recommended Dosage in Pediatric Patients (0–3 months of age)

EMTRIVA oral solution: 3 mg per kg administered once daily orally.

Recommended Dosage in Pediatric Patients (3 months through 17 years of age)

EMTRIVA oral solution: 6 mg per kg up to a maximum of 240 mg (24 mL) administered once daily orally.

EMTRIVA capsules: For pediatric patients weighing more than 33 kg who can swallow an intact capsule, one 200 mg capsule administered once daily orally.

Dosage Adjustment in Patients with Renal Impairment

Table 1 provides dosage interval adjustment for patients with renal impairment. No dosage adjustment is necessary for patients with mild renal impairment (creatinine clearance 50–80 mL/min). The safety and effectiveness of dose adjustment recommendations in patients with moderate to severe renal impairment (creatinine clearance below 50 mL/min) have not been clinically evaluated. Therefore, clinical response to treatment and renal function should be closely monitored in these patients.

Table 1 Dose Interval Adjustment for Adult Patients with Altered Creatinine Clearance
	Creatinine Clearance (mL/min)
Formulation	≥50 mL/min	30–49 mL/min	15–29 mL/min	<15 mL/min or on hemodialysis*
* Hemodialysis Patients: If dosing on day of dialysis, give dose after dialysis.
Capsule (200 mg)	200 mg every 24 hours	200 mg every 48 hours	200 mg every 72 hours	200 mg every 96 hours
Oral Solution (10 mg/mL)	240 mg every 24 hours (24 mL)	120 mg every 24 hours (12 mL)	80 mg every 24 hours (8 mL)	60 mg every 24 hours (6 mL)