Skip to main content

Nucleoside reverse transcriptase inhibitors (NRTIs)

What are Nucleoside reverse transcriptase inhibitors (NRTIs)?

Nucleoside reverse transcriptase inhibitors (NRTIs) are active inhibitors of reverse transcriptase found in retroviruses such as the human immunodeficiency virus (HIV). The different nucleoside reverse transcriptase inhibitors may be activated differently but they have the same mechanism of action. NRTIs are activated generally by phosphorylation to the triphosphate form by cellular enzymes. It then competes with cellular triphosphates, which are substrates for proviral DNA by viral reverse transcriptase. NRTIs are used in the treatment of human immunodeficiency virus (HIV infection) and acquired immune deficiency syndrome (AIDS).

List of Nucleoside reverse transcriptase inhibitors (NRTIs):

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Viread (Pro)
Generic name: tenofovir
8.0
13 reviews
Vemlidy (Pro)
Generic name: tenofovir alafenamide
8.0
1 review
Epivir-HBV (Pro)
Generic name: lamivudine
10
1 review
Epivir (Pro)
Generic name: lamivudine
7.0
1 review
Baraclude (Pro)
Generic name: entecavir
10
1 review
Ziagen (Pro)
Generic name: abacavir
8.0
No reviews
Zerit (Pro)
Generic name: stavudine
1.0
No reviews
Videx EC (Pro)
Generic name: didanosine
No reviews
Videx (Pro)
Generic name: didanosine
9.0
No reviews
Tyzeka (Pro)
Generic name: telbivudine
No reviews
Retrovir (Pro)
Generic name: zidovudine
1.0
No reviews
Hivid
Generic name: zalcitabine
No reviews
Hepsera (Pro)
Generic name: adefovir
10
No reviews
Emtriva (Pro)
Generic name: emtricitabine
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See Also

Medical conditions associated with nucleoside reverse transcriptase inhibitors (NRTIs):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.