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Emerphed Dosage

Generic name: Ephedrine Sulfate 5mg in 1mL
Dosage form: injection
Drug class: Vasopressors

Medically reviewed by Last updated on Mar 1, 2023.

General Dosage and Administration Instructions

  • This is a premixed formulation. Do not dilute prior to use.
  • Discard any unused portion of EMERPHED.
  • Inspect parenteral drug products visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
  • The single-dose prefilled syringe is intended for use in one patient during one surgical procedure.

EMERPHED is a clear, colorless solution. Do not use if the solution is not clear or if particulate matter is present.

Dosing for the Treatment of Clinically Important Hypotension in the Setting of Anesthesia

The recommended dosages for the treatment of clinically important hypotension in the setting of anesthesia is an initial dose of 5 mg to 10 mg administered by intravenous bolus. Administer additional boluses as needed, not to exceed a total dosage of 50 mg.

  • Adjust dosage according to the blood pressure goal (i.e., titrate to effect).

Instructions for Use of Prefilled Syringe

The proper method of administration of EMERPHED injection is described in the following instructions.

For each single-dose prefilled syringe:

  1. Remove syringe from tray and check that it is not damaged or leaking.
  2. Inspect drug product in glass syringe for any visible particulate matter or discoloration prior to use. Discard if particulate matter or discoloration is present.
  3. Do not remove the tamper evident seal. Push plunger rod slightly in to break the stopper loose while tip cap is still on.
  4. Hold the syringe upright on the syringe barrel (C). With the other hand, take hold of the cap (A) and twist off cap counterclockwise from syringe tip (see Figure 1).

    Figure 1

  5. Once cap (A) is off, DO NOT TOUCH THE STERILE SYRINGE TIP (Luer-Lok) (B) (see Figure 2).

    Figure 2

  6. Discard the tip cap.
  7. Expel air bubble.
  8. Adjust dose into sterile material (if applicable).
  9. Connect the syringe to an appropriate intravenous connection.
    • Before injection, ensure that the syringe is securely attached to the needle or needleless luer access device (NLAD).
  10. Depress plunger rod to deliver medication. Ensure that pressure is maintained on the plunger rod during the entire administration.
  11. Remove syringe from NLAD (if applicable) and discard into appropriate receptacle.
    • To prevent needle stick injuries, do not recap needle when needle is connected to syringe.

    NOTE: All steps must be done sequentially

    • Do not re-sterilize syringe
    • Do not use this product on a sterile field
    • Do not introduce any other fluid into the syringe at any time
    • This product is for single dose only

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.