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Carbamide Peroxide Topical Dosage

Applies to the following strengths: 10%; 15%

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Periodontitis

10% liquid:
Direct application: Apply several drops to the affected area up to 4 times a day AND at bedtime (or as directed)
Oral rinse: Apply 10 to 20 drops onto the tongue and swish up to 4 times a day AND at bedtime (or as directed)
Duration of therapy: Up to 7 days

Comments:
-Patients should avoid swallowing this drug.
-Direct application: Patients should retain this drug for approximately 2 to 3 minutes.
-Oral rinse: Patients should mix the drops with saliva, then they should swish the mixture around for at least 1 minute.

Uses:
-Aiding in the removal of mucus, phlegm, or other secretions associated with occasional sore mouth
-Temporary use in cleansing canker sores
-Temporary use in cleansing gum inflammation or minor wounds from accidental injuries, dental procedures, dentures, orthodontic appliances, or other gum/mouth irritations

Usual Pediatric Dose for Periodontitis

2 years and older:
10% liquid:
Direct application: Apply several drops to the affected area up to 4 times a day AND at bedtime (or as directed)
Oral rinse: Apply 10 to 20 drops onto the tongue and swish up to 4 times a day AND at bedtime (or as directed)
Duration of therapy: Up to 7 days

Comments:
-Patients should avoid swallowing this drug; those under 12 years should be supervised during use.
-Direct application: Patients should retain this drug for approximately 2 to 3 minutes.
-Oral rinse: Patients should mix the drops with saliva, then they should swish the mixture around for at least 1 minute.

Uses:
-Aiding in the removal of mucus, phlegm, or other secretions associated with occasional sore mouth
-Temporary use in cleansing canker sores
-Temporary use in cleansing gum inflammation or minor wounds from accidental injuries, dental procedures, dentures, orthodontic appliances, or other gum/mouth irritations

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS: None.

Safety and efficacy of the 10% solution have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Patients should not ingest this drug.
-Contact with the eyes and skin should be avoided.

Storage requirements:
-The bottle should be capped when not in use.

Reconstitution/preparation techniques:
-Do not dilute.

General:
-LIMITATION OF USE: This drug should be limited to oral use only.

Monitoring:
-HYPERSENSITIVITY: Excessive sensitivity/irritation

Patient advice:
-Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
-Patients should be instructed to stop treatment and to contact their healthcare provider if symptoms do not improve within 7 days OR if excessive sensitivity/irritation occur during treatment.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.