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Brimonidine Topical Dosage

Medically reviewed by Last updated on Sep 12, 2023.

Applies to the following strengths: 0.33%; 0.25%

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Acne Rosacea

Apply a pea-sized amount once a day to the central forehead, chin, nose, and each cheek


  • Patients should wash their hands after applying this drug.
  • This drug is not for oral, ophthalmic, or intravaginal use.
  • Patients should apply the treatment in a smooth, thin layer across the entire face, avoiding the nose and mouth.

Use: Topical treatment of persistent (nontransient) facial erythema of rosacea

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

  • Apply smoothly and evenly across the entire face avoiding the eyes, eyelids, lips, mouth and membrane of the inner nose.
  • It can be used in conjunction with other cutaneous drugs for the treatment of inflammatory lesions of rosacea and with cosmetics. These other drugs should not be applied immediately before the daily application of this drug; they may be used only after the applied treatment has dried.

Storage requirements:
  • Store below 25C; do not freeze.

  • Treatment should be reserved to patients with a definitive diagnosis of rosacea.

Patient advice:
  • Skin redness may occur 3 to 4 hours after application. If erythema worsens, patients should be instructed to contact their healthcare provider.
  • Patients should be told to keep this drug out of the reach of children.
  • Patients should be advised to avoid using more than 5 pea-sized amounts per day AND to avoid using this drug more than once a day.
  • Patients should be advised to speak to a healthcare provider if they are pregnant, intend to become pregnant, or are breastfeeding.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.