Acetaminophen / Dextromethorphan / Doxylamine / Phenylephrine Dosage
Medically reviewed by Drugs.com. Last updated on Dec 3, 2018.
Applies to the following strengths: 250 mg-10 mg-6.25 mg-5 mg; 650 mg-20 mg-12.5 mg-10 mg/30 mL; 325 mg-10 mg-6.25 mg-5 mg; 325 mg-10 mg-6.25 mg-5 mg/15 mL
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Cold Symptoms
Acetaminophen/dextromethorphan/doxylamine/PE 250 mg-10 mg-6.25 mg-5 mg oral tablet, effervescent:
2 tablets at bedtime (may be taken up to every 4 hours). Dissolve tablets in 4 ounces of water.
Maximum dose: 8 tablets in 24 hours.
Acetaminophen/dextromethorphan/doxylamine/PE 325 mg-10 mg-6.25 mg-5 mg/15 mL oral liquid:
30 mL orally every 4 hours
Maximum dose: 180 mL in 24 hours
Acetaminophen/dextromethorphan/doxylamine/PE 650 mg-20 mg-12.5 mg-10 mg/30 mL oral liquid:
30 mL orally every 4 hours
Maximum dose: 120 mL (4 doses) in 24 hours
Usual Pediatric Dose for Cold Symptoms
12 years and older:
Acetaminophen/dextromethorphan/doxylamine/PE 250 mg-10 mg-6.25 mg-5 mg oral tablet, effervescent:
2 tablets at bedtime (may be taken up to every 4 hours). Dissolve tablets in 4 ounces of water.
Maximum dose: 8 tablets in 24 hours.
Acetaminophen/dextromethorphan/doxylamine/PE 325 mg-10 mg-6.25 mg-5 mg/15 mL oral liquid:
30 mL orally every 4 hours
Maximum dose: 180 mL in 24 hours
Acetaminophen/dextromethorphan/doxylamine/PE 650 mg-20 mg-12.5 mg-10 mg/30 mL oral liquid:
30 mL orally every 4 hours
Maximum dose: 120 mL (4 doses) in 24 hours
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Each tablet contains 477 mg sodium and 5.8 mg phenylalanine.
Dialysis
Data not available
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about acetaminophen/dextromethorphan/doxylamine/phenylephrine
- Side Effects
- During Pregnancy
- Drug Interactions
- 1 Review
- Drug class: upper respiratory combinations
- FDA Alerts (3)
Consumer resources
- Acetaminophen, dextromethorphan, doxylamine, and phenylephrine
- Acetaminophen, Doxylamine, Dextromethorphan, and Phenylephrine Liquid
Other brands: Vicks NyQuil Severe Cold & Flu, Delsym Night Time Multi-Symptom, Tylenol Cold Multi-Symptom Nighttime Liquid
