Acetaminophen / Dextromethorphan / Doxylamine / Phenylephrine Dosage

Medically reviewed on December 1, 2017.

Usual Adult Dose for Cold Symptoms

Acetaminophen/dextromethorphan/doxylamine/PE 250 mg-10 mg-6.25 mg-5 mg oral tablet, effervescent:
2 tablets at bedtime (may be taken up to every 4 hours). Dissolve tablets in 4 ounces of water.
Maximum dose: 8 tablets in 24 hours.
Acetaminophen/dextromethorphan/doxylamine/PE 325 mg-10 mg-6.25 mg-5 mg/15 mL oral liquid:
30 mL orally every 4 hours
Maximum dose: 180 mL in 24 hours
Acetaminophen/dextromethorphan/doxylamine/PE 650 mg-20 mg-12.5 mg-10 mg/30 mL oral liquid:
30 mL orally every 4 hours
Maximum dose: 120 mL (4 doses) in 24 hours

Usual Pediatric Dose for Cold Symptoms

12 years and older:
Acetaminophen/dextromethorphan/doxylamine/PE 250 mg-10 mg-6.25 mg-5 mg oral tablet, effervescent:
2 tablets at bedtime (may be taken up to every 4 hours). Dissolve tablets in 4 ounces of water.
Maximum dose: 8 tablets in 24 hours.
Acetaminophen/dextromethorphan/doxylamine/PE 325 mg-10 mg-6.25 mg-5 mg/15 mL oral liquid:
30 mL orally every 4 hours
Maximum dose: 180 mL in 24 hours
Acetaminophen/dextromethorphan/doxylamine/PE 650 mg-20 mg-12.5 mg-10 mg/30 mL oral liquid:
30 mL orally every 4 hours
Maximum dose: 120 mL (4 doses) in 24 hours

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Each tablet contains 477 mg sodium and 5.8 mg phenylalanine.

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer