Acetaminophen/dextromethorphan/doxylamine/phenylephrine Interactions
There are 666 drugs known to interact with acetaminophen/dextromethorphan/doxylamine/phenylephrine, along with 15 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 102 are major, 549 are moderate, and 15 are minor.
- View all 666 medications that may interact with acetaminophen/dextromethorphan/doxylamine/phenylephrine
- View acetaminophen/dextromethorphan/doxylamine/phenylephrine alcohol/food interactions (2)
- View acetaminophen/dextromethorphan/doxylamine/phenylephrine disease interactions (15)
Most frequently checked interactions
View interaction reports for acetaminophen / dextromethorphan / doxylamine / phenylephrine and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- Acidophilus (lactobacillus acidophilus)
- Acidophilus Probiotic Blend (lactobacillus acidophilus)
- Adderall (amphetamine / dextroamphetamine)
- Advair HFA (fluticasone / salmeterol)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Advil PM (diphenhydramine / ibuprofen)
- Afluria Quadrivalent (influenza virus vaccine, inactivated)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Alka-Seltzer Plus Maximum Strength Cold & Cough (acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine)
- Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels (acetaminophen / dextromethorphan / phenylephrine)
- Allegra (fexofenadine)
- Allegra Allergy (fexofenadine)
- Allegra-D 24 Hour Allergy & Congestion (fexofenadine / pseudoephedrine)
- Amitiza (lubiprostone)
- Augmentin (amoxicillin / clavulanate)
- Augmentin XR (amoxicillin / clavulanate)
- Azo-Cranberry (cranberry)
- Backaid Max (acetaminophen / pamabrom)
- Bayer Back & Body (aspirin / caffeine)
- Benadryl (diphenhydramine)
- Crestor (rosuvastatin)
- Flonase (fluticasone nasal)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Promethazine DM (dextromethorphan / promethazine)
- Robitussin Nighttime Cough DM (dextromethorphan / doxylamine)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Acetaminophen/dextromethorphan/doxylamine/phenylephrine alcohol/food interactions
There are 2 alcohol/food interactions with acetaminophen / dextromethorphan / doxylamine / phenylephrine.
Acetaminophen/dextromethorphan/doxylamine/phenylephrine disease interactions
There are 15 disease interactions with acetaminophen / dextromethorphan / doxylamine / phenylephrine which include:
- alcoholism
- liver disease
- depression
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- BPH
- diabetes
- glaucoma
Report options
More about acetaminophen / dextromethorphan / doxylamine / phenylephrine
- acetaminophen/dextromethorphan/doxylamine/phenylephrine consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (3)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
