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Patiromer Disease Interactions

There are 2 disease interactions with patiromer.

Major

Patiromer (applies to patiromer) gastrointestinal motility

Major Potential Hazard, Moderate plausibility. Applicable conditions: Gastrointestinal Obstruction, Constipation

The use of patiromer should be avoided in patients with severe constipation, bowel obstruction or impaction, including abnormal post-operative bowel motility disorders, as this agent may be ineffective and may worsen gastrointestinal conditions. Therapy with patiromer should be administered cautiously in patients with a history of bowel obstruction or major gastrointestinal surgery, severe gastrointestinal disorders, or swallowing disorders.

Moderate

Patiromer (applies to patiromer) hypomagnesemia

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Diarrhea, Magnesium Imbalance

Patiromer binds to magnesium in the colon, which can lead to hypomagnesemia. It is recommended to monitor serum magnesium concentrations during therapy. Therapy with patiromer should be administered cautiously in patients with or predisposed to magnesium deficiency. Consider magnesium supplementation in patients who develop low serum magnesium levels.

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Patiromer drug interactions

There are 104 drug interactions with patiromer.

Patiromer alcohol/food interactions

There are 2 alcohol/food interactions with patiromer.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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