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Nitropress Disease Interactions

There are 7 disease interactions with Nitropress (nitroprusside).

Major

Nitroprusside (applies to Nitropress) cerebral vascular insufficiency

Major Potential Hazard, High plausibility. Applicable conditions: Cerebral Vascular Disorder

The use of nitroprusside is contraindicated in patients with cerebral vascular insufficiency.

References

  1. "Product Information. Nipride RTU (sodium nitroprusside)." Roche Laboratories
Major

Nitroprusside (applies to Nitropress) compensatory hypertension

Major Potential Hazard, High plausibility. Applicable conditions: Aortic Coarctation, Arteriovenous Shunting

Nitroprusside should not be used for the treatment of compensatory hypertension, such as that associated with aortic coarctation or arteriovenous shunt.

References

  1. "Product Information. Nipride RTU (sodium nitroprusside)." Roche Laboratories
Major

Nitroprusside (applies to Nitropress) congenital optic atrophy

Major Potential Hazard, High plausibility. Applicable conditions: Leber's Disease

The use of nitroprusside is contraindicated in patients with defective or absent rhodanase activity, such as patients with congenital (Leber's) optic atrophy or with tobacco amblyopia.

References

  1. "Product Information. Nipride RTU (sodium nitroprusside)." Roche Laboratories
Major

Nitroprusside (applies to Nitropress) sepsis

Major Potential Hazard, Moderate plausibility. Applicable conditions: Peripheral Arterial Disease

Sodium nitroprusside should not be used for the treatment of acute congestive heart failure associated with reduced peripheral vascular resistance such as high- output heart failure that may be seen in endotoxic sepsis.

References

  1. "Product Information. Nipride RTU (sodium nitroprusside)." Roche Laboratories
Moderate

Nitroprusside (applies to Nitropress) anemia

Moderate Potential Hazard, Moderate plausibility.

When sodium nitroprusside is used to control hypotension during anesthesia, the patient's capacity to compensate for anemia and hypovolemia may be diminished. If possible, preexisting anemia and hypovolemia should be corrected prior to administration of sodium nitroprusside.

References

  1. "Product Information. Nipride RTU (sodium nitroprusside)." Roche Laboratories
Moderate

Nitroprusside (applies to Nitropress) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Use caution when administering sodium nitroprusside to patients with hepatic insufficiency.

References

  1. "Product Information. Nipride RTU (sodium nitroprusside)." Roche Laboratories
Moderate

Nitroprusside (applies to Nitropress) intracranial hypertension

Moderate Potential Hazard, Moderate plausibility.

Like other vasodilators, sodium nitroprusside can cause increases in intracranial pressure. In patients whose intracranial pressure is already elevated, sodium nitroprusside should be used only with extreme caution.

References

  1. "Product Information. Nipride RTU (sodium nitroprusside)." Roche Laboratories

Nitropress drug interactions

There are 217 drug interactions with Nitropress (nitroprusside).

Nitropress alcohol/food interactions

There is 1 alcohol/food interaction with Nitropress (nitroprusside).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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