LoSo Prep Bowel Cleansing System (bisacodyl / magnesium citrate) Disease Interactions
There is 1 disease interaction with LoSo Prep Bowel Cleansing System (bisacodyl / magnesium citrate):
Magnesium Salts (Includes LoSo Prep Bowel Cleansing System) ↔ Renal Dysfunction
Severe Potential Hazard, High plausibility
Applies to: Renal Dysfunction
Magnesium is eliminated by the kidney. The serum concentration of magnesium is increased in patients with renal impairment. Magnesium toxicity includes CNS depression, muscular paralysis, respiratory depression, hypotension and prolonged cardiac conduction time. Disappearance of the patellar reflex is a useful clinical sign of magnesium intoxication. Therapy with magnesium should be administered cautiously and dosages should be modified in patients with compromised renal function. Clinical monitoring of serum magnesium levels is recommended.
References
- "Product Information. Mag-Ox 400 (magnesium oxide)." Blaine, Erlanger, KY.
- "Product Information. Uro-Mag (magnesium oxide)." Blaine, Erlanger, KY.
- "Product Information. Losospan (magaldrate)." Whitehall-Robbins, Madison, NJ.
LoSo Prep Bowel Cleansing System (bisacodyl / magnesium citrate) drug Interactions
There are 325 drug interactions with LoSo Prep Bowel Cleansing System (bisacodyl / magnesium citrate)
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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