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Coartem (artemether / lumefantrine) Disease Interactions

There is 1 disease interaction with Coartem (artemether / lumefantrine):

Major

Antimalarial agents (Includes Coartem) ↔ QT prolongation

Severe Potential Hazard, Moderate plausibility. Applies to: Magnesium Imbalance, Hypokalemia, Arrhythmias

The use of certain antimalarial agents is contraindicated in patients with known prolongation of QT interval as they can develop fatal arrhythmias. It should also be avoided in patients with clinical conditions known to prolong the QT interval, such as a congenital prolongation of the QT interval or sudden death, uncorrected hypokalemia or hypomagnesemia, bradycardia, and certain cardiac conditions. Caution is advised in patients taking other medications that can prolong the QT interval.

References

  1. "Product Information. Quinine (quinine)." Zenith Goldline Pharmaceuticals, Fort Lauderdale, FL.

Coartem (artemether / lumefantrine) drug interactions

There are 581 drug interactions with Coartem (artemether / lumefantrine)

Coartem (artemether / lumefantrine) alcohol/food interactions

There is 1 alcohol/food interaction with Coartem (artemether / lumefantrine)

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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