Medically reviewed on June 7, 2018
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Antibiotic
Pharmacologic Class: 2nd Generation Cephalosporin
Uses For This Medicine
Cefotetan injection is used to treat bacterial infections in many different parts of the body. Cefotetan is also given before certain types of surgery to prevent infections.
Cefotetan injection belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, cefotetan will not work for colds, flu, or other virus infections.
Cefotetan is available only with your doctor's prescription.
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For cefotetan, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to cefotetan or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of cefotetan injection in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cefotetan injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cefotetan injection.
|All Trimesters||B||Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving cefotetan, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using cefotetan with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Cholera Vaccine, Live
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using cefotetan with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use cefotetan, or give you special instructions about the use of food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of cefotetan. Make sure you tell your doctor if you have any other medical problems, especially:
- Colitis (inflammation in gut), history of or
- Diarrhea, severe, history of or
- Hemolytic anemia or
- Seizures—Use with caution. May make these conditions worse.
- Kidney disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.
Proper Use of This Medicine
A nurse or other trained health professional will give you cefotetan. Cefotetan is given as a shot into one of your muscles, or through a needle placed in one of your veins.
Precautions While Using This Medicine
If your symptoms do not improve within a few days, or if they become worse, check with your doctor.
Hemolytic anemia may occur while you are using cefotetan. Stop using cefotetan and check with your doctor right away if you have back, leg, or stomach pains; bleeding gums; chills; dark urine; difficulty with breathing; fever; general body swelling; headache; loss of appetite; nausea or vomiting; nosebleeds; pale skin; sore throat; unusual tiredness or weakness; or yellowing of the eyes or skin.
Cefotetan injection may cause diarrhea, and in some cases it can be severe. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.
Do not drink alcohol while you are receiving cefotetan injection and for 3 days (72 hours) after your last dose. Drinking alcohol during this period may cause flushing; headache; sweating; and fast, pounding, or irregular heartbeat.
Before you have any medical tests, tell the medical doctor in charge that you are receiving cefotetan. The results of some tests may be affected by cefotetan.
This Medicine Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
- Abdominal or stomach cramps or tenderness
- back, leg, or stomach pains
- black, tarry stools
- bleeding gums
- chest pain
- dark urine
- diarrhea, watery and severe, which may also be bloody
- difficulty with breathing
- general body swelling
- increased thirst
- loss of appetite
- nausea or vomiting
- painful or difficult urination
- pale skin
- shortness of breath
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- swollen glands
- unusual bleeding or bruising
- unusual tiredness or weakness
- unusual weight loss
- yellowing of the eyes or skin
- Blood in the urine
- bluish color
- change in frequency of urination or amount of urine
- changes in skin color
- increased thirst
- swelling of the feet or lower legs
Incidence not known
- Blistering, peeling, or loosening of the skin
- cough or hoarseness
- coughing up blood
- difficulty with swallowing
- fast heartbeat
- fever with or without chills
- general feeling of tiredness or weakness
- high fever
- increased menstrual flow or vaginal bleeding
- itching of the vagina or genital area
- joint or muscle pain
- lower back or side pain
- pain during sexual intercourse
- pinpoint red spots on the skin
- prolonged bleeding from cuts
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- red or black, tarry stools
- red or dark brown urine
- red skin lesions, often with a purple center
- red, irritated eyes
- skin rash
- sudden decrease in the amount of urine
- swollen or painful glands
- thick, white vaginal discharge with no odor or with a mild odor
- tightness in the chest
- unpleasant breath odor
- vomiting of blood
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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- Drug class: second generation cephalosporins
Other brands: Cefotan