Ruxolitinib Alternatives Compared
Ruxolitinib | Hydroxyurea | Jakafi |
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Ruxolitinib | Hydroxyurea | Jakafi (ruxolitinib) |
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Prescription only
Prescribed for Myelofibrosis, Polycythemia Vera, Graft-versus-host disease, Myeloproliferative Disorders. ruxolitinib may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Chronic Myelogenous Leukemia, Sickle Cell Anemia, Head and Neck Cancer, Cervical Cancer, Glioblastoma Multiforme, Plaque Psoriasis, Polycythemia Vera, Psoriasis, Psoriatic Arthritis... View more |
Prescription only
Prescribed for Myelofibrosis, Polycythemia Vera, Graft-versus-host disease, Myeloproliferative Disorders. Jakafi may also be used for purposes not listed in this medication guide. |
Related suggestions Polycythemia Vera
Popular comparisons
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More about Ruxolitinib | More about Hydroxyurea | More about Jakafi (ruxolitinib) | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
Ruxolitinib has an average rating of 7.3 out of 10 from a total of 41 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 18% reported a negative effect. |
Hydroxyurea has an average rating of 7.0 out of 10 from a total of 45 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 23% reported a negative effect. |
Jakafi has an average rating of 7.4 out of 10 from a total of 33 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 16% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: Ruxolitinib side effects in more detail. |
See also: Hydroxyurea side effects in more detail. |
See also: Jakafi side effects in more detail. |
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Generic Availability | ||||||||||||||||||
N/A |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Hydroxyurea prices |
View all Jakafi prices |
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Dosage Forms Available | ||||||||||||||||||
N/A |
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Brand Names | ||||||||||||||||||
Jakafi | Droxia, Hydrea, Siklos, Xromi |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
5.8 hours |
4 hours |
5.8 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 493 drugs are known to interact with Ruxolitinib:
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A total of 279 drugs are known to interact with Hydroxyurea:
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A total of 493 drugs are known to interact with Jakafi:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||
First Approval Date | ||||||||||||||||||
November 16, 2011 |
December 07, 1967 |
November 16, 2011 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.