Ruconest Alternatives Compared
Ruconest (conestat alfa) | Orladeyo (berotralstat) | Andembry (garadacimab) |
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Ruconest (conestat alfa) | Orladeyo (berotralstat) | Andembry (garadacimab) |
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Prescription only
Ruconest is used to treat hereditary angioedema (HAE) in adults and adolescents and is given by slow intravenous injection over 5 minutes, usually by a healthcare professional. Headache, nausea, and... View more |
Prescription only
Orladeyo is an oral, once-daily medication used to prevent angioedema attacks in adults and children 12 years and older with HAE. It is the only oral preventive treatment for HAE attacks currently... View more |
Prescription only
Prescribed for Hereditary Angioedema. Andembry may also be used for purposes not listed in this medication guide. |
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More about Ruconest (conestat alfa) | More about Orladeyo (berotralstat) | More about Andembry (garadacimab) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Ruconest has an average rating of 10.0 out of 10 from a total of 3 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Orladeyo has an average rating of 6.7 out of 10 from a total of 3 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 0% reported a negative effect. |
Be the first to share your experience with this drug. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Ruconest side effects |
View all Orladeyo side effects |
View all Andembry side effects |
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Drug Class | ||||||||||||||||||||||||||
Generic Availability | ||||||||||||||||||||||||||
N/A |
N/A |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Ruconest prices |
View all Orladeyo prices |
View all Andembry prices |
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Dosage Forms | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
3 hours |
152 hours |
417.6 hours |
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CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 50 drugs are known to interact with Ruconest:
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A total of 524 drugs are known to interact with Orladeyo:
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A total of 3 drugs are known to interact with Andembry:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
N/A |
December 03, 2020 |
June 16, 2025 |
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WADA Class View classifications | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient Resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
N/A |
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Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.