Orladeyo Dosage
Generic name: Berotralstat hydrochloride 150mg
Dosage form: capsule
Drug class: Hereditary angioedema agents
Medically reviewed by Drugs.com. Last updated on Nov 29, 2023.
Recommended Dosage
The recommended dosage of ORLADEYO is one 150 mg capsule taken orally once daily with food.
Recommended Dosage in Patients with Hepatic Impairment
No dosage adjustment of ORLADEYO is recommended for patients with mild hepatic impairment (Child-Pugh Class A) [see Use in Specific Populations (8.7) and Clinical Pharmacology (12.3)].
In patients with moderate or severe hepatic impairment (Child-Pugh B or C), the recommended dosage of ORLADEYO is one 110 mg capsule taken orally once daily with food [see Use in Specific Populations (8.7) and Clinical Pharmacology (12.3)].
Dosage Adjustment in Patients with Persistent GI Reactions
Gastrointestinal (GI) reactions may occur in patients receiving ORLADEYO [see Adverse Reactions (6.1)]. If GI events persist, a reduced dose of 110 mg once daily with food may be considered.
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