Orladeyo Disease Interactions
There is 1 disease interaction with Orladeyo (berotralstat).
Berotralstat (applies to Orladeyo) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Berotralstat has not been studied in patients with end-stage renal disease (CrCl < 15 mL/min or patients requiring hemodialysis), and its use is not recommended in these patients. No dosage adjustment is recommended for patients with mild, moderate or severe renal impairment.
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Orladeyo drug interactions
There are 520 drug interactions with Orladeyo (berotralstat).
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- Drug class: hereditary angioedema agents
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Takhzyro
Takhzyro (lanadelumab-flyo) is used to prevent hereditary angioedema (HAE) and reduce symptoms ...
Firazyr
Firazyr is used to treat acute attacks of hereditary angioedema (HAE) in adults. It can be ...
Haegarda
Haegarda is an injectable protein replacement therapy that prevents swelling and attacks in ...
Berinert
Berinert is used to treat acute abdominal, facial, or laryngeal hereditary angioedema (HAE) attacks ...
Cinryze
Cinryze (complement C1 esterase inhibitor) is used to prevent attacks of angioedema in people with ...
Ruconest
Ruconest is used to treat angioedema attacks in adult and adolescent patients with Hereditary ...
Kalbitor
Kalbitor is used to treat acute attacks of hereditary angioedema (HAE) in patients 12 years and ...
Lanadelumab
Lanadelumab injection is a monoclonal antibody used to prevent hereditary angioedema. Includes side ...
Icatibant
Icatibant is an injection used to treat acute attacks of hereditary angioedema (HAE) in adults. It ...
Stanozolol
Stanozolol is used in the treatment of hereditary angioedema, which causes episodes of swelling of ...
Further information
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