Comparing Protonix vs Nexium
Protonix | Nexium |
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Protonix (pantoprazole) | Nexium (esomeprazole) |
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Prescription only
Protonix is used for the treatment of conditions associated with excessive acid production in the esophagus and stomach. Long-term use may be associated with magnesium and vitamin B12 deficiency and... View more |
Prescription only
Nexium effectively heals inflamed tissue in the gastrointestinal tract and relieves symptoms of heartburn. Nexium is available orally and as an IV preparation that may be used in adults and children... View more |
Related suggestions Helicobacter Pylori Infection
Erosive Esophagitis
Barrett's Esophagus
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More about Protonix (pantoprazole) | More about Nexium (esomeprazole) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Protonix has an average rating of 7.3 out of 10 from a total of 83 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 22% reported a negative effect. |
Nexium has an average rating of 6.1 out of 10 from a total of 209 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 35% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Protonix side effects in more detail. |
See also: Nexium side effects in more detail. |
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Generic Availability | |||||||||||||||||
Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Protonix prices |
View all Nexium prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other pantoprazole brands include: Protonix IV | Other esomeprazole brands include: Nexium 24HR, Nexium IV | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
1 hour |
1.5 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 167 drugs are known to interact with Protonix:
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A total of 200 drugs are known to interact with Nexium:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
February 02, 2000 |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.