Comparing Otezla vs Simponi
Otezla | Simponi |
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Otezla (apremilast) | Simponi (golimumab) |
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Prescription only
Otezla is a PDE4 inhibitor that may be used to treat plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It has been associated with severe diarrhea, nausea, and v... View more |
Prescription only
Prescribed for Ankylosing Spondylitis, Psoriatic Arthritis, Rheumatoid Arthritis, Spondyloarthritis, Ulcerative Colitis. Simponi may also be used for purposes not listed in this medication guide. |
Related suggestions Psoriatic Arthritis
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More about Otezla (apremilast) | More about Simponi (golimumab) | ||||||||
Ratings & Reviews | |||||||||
Otezla has an average rating of 5.1 out of 10 from a total of 429 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 42% reported a negative effect. |
Simponi has an average rating of 6.3 out of 10 from a total of 114 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 30% reported a negative effect. |
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Drug Class | |||||||||
Side Effects | |||||||||
See also: Otezla side effects in more detail. |
See also: Simponi side effects in more detail. |
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Generic Availability | |||||||||
N/A |
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Pricing and Coupons * Prices are without insurance | |||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Simponi prices |
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Dosage Form(s) Available | |||||||||
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Brand Names | |||||||||
N/A |
Other golimumab brands include: Simponi Aria | ||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
9 hours |
336 hours |
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CSA Schedule ** View glossary of terms | |||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 86 drugs are known to interact with Otezla:
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A total of 480 drugs are known to interact with Simponi:
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Alcohol/Food/Lifestyle Interactions | |||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||
First Approval Date | |||||||||
March 21, 2014 |
April 24, 2009 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||
N/A |
N/A |
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More Information | |||||||||
Patient resources | |||||||||
Professional Resources | |||||||||
Related Treatment Guide | |||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.