Comparing Melatonin vs Zolpidem
| Melatonin | Zolpidem |
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| Melatonin | Zolpidem |
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Prescription and OTC
Supplemental melatonin is very effective at reducing symptoms of jet lag, particularly that brought about by eastward travel across five or more time zones. Melatonin may also be used to treat sleep... View more |
Prescription only
Zolpidem induces sleep; however, longer-acting formulations may impair physical and mental capabilities the next day. May induce complex or dangerous sleep-related behaviors like "sleep-driving"... View more |
Related suggestions Insomnia
Popular comparisons
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| More about Melatonin | More about Zolpidem | ||||||||
| Ratings & Reviews | |||||||||
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Melatonin has an average rating of 5.7 out of 10 from a total of 239 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 37% reported a negative effect. |
Zolpidem has an average rating of 6.9 out of 10 from a total of 1060 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Melatonin side effects |
View all Zolpidem side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Zolpidem prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Bio-Melatonin, Melatonin Time Release, SGard, Sleep3 | Ambien, Ambien CR, Edluar, Zolpimist | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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N/A |
2.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||
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Category N
Not classified
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 342 drugs are known to interact with Melatonin:
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A total of 482 drugs are known to interact with Zolpidem:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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N/A |
December 16, 1992 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.