Comparing Melatonin vs Sertraline
| Melatonin | Sertraline |
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| Melatonin | Sertraline |
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Prescription and OTC
Supplemental melatonin is very effective at reducing symptoms of jet lag, particularly that brought about by eastward travel across five or more time zones. Melatonin may also be used to treat sleep... View more |
Prescription only
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the... View more |
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| More about Melatonin | More about Sertraline | ||||||||
| Ratings & Reviews | |||||||||
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Melatonin has an average rating of 5.7 out of 10 from a total of 239 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 37% reported a negative effect. |
Sertraline has an average rating of 7.3 out of 10 from a total of 4567 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Melatonin side effects |
View all Sertraline side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Sertraline prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Bio-Melatonin, Melatonin Time Release, SGard, Sleep3 | Zoloft | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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N/A |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category N
Not classified
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 342 drugs are known to interact with Melatonin:
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A total of 673 drugs are known to interact with Sertraline:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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N/A |
December 30, 1991 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.