Comparing Melatonin vs Sertraline
| Melatonin | Sertraline |
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| Melatonin | Sertraline |
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Prescription and OTC
Melatonin is a supplement that is used short-term to help with sleeping, including insomnia due to non-24-hour sleep wake disorder, shift work sleep disorders, or REM sleep behavior disorder. It... View more |
Prescription only
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the... View more |
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| More about Melatonin | More about Sertraline | ||||||||
| Ratings & Reviews | |||||||||
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Melatonin has an average rating of 5.7 out of 10 from a total of 240 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 37% reported a negative effect. |
Sertraline has an average rating of 7.3 out of 10 from a total of 4599 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Melatonin side effects |
View all Sertraline side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Sertraline prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Bio-Melatonin, Melatonin Time Release, SGard, Sleep3 | Zoloft | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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N/A |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category N
Not classified
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 345 drugs are known to interact with Melatonin:
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A total of 675 drugs are known to interact with Sertraline:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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N/A |
December 30, 1991 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.