Tacrolimus User Reviews & Ratings (Page 2)
Brand names: Prograf, Envarsus XR, Astagraf XL
Tacrolimus has an average rating of 7.6 out of 10 from a total of 51 reviews on Drugs.com. 69% of reviewers reported a positive experience, while 14% reported a negative experience.
Reviews for Tacrolimus
- Nep...
- Taken for 5 to 10 years
- April 20, 2018
For Nephrotic Syndrome "My son has been on tacrolimus for 5 years. He is 14 and has Nephrotic syndrome, never had a transplant, and his urine always shows that he has protein leaking when results come back. When the doctor sees him, he looks fine, but when the labs come back, they're not good. I read all the reviews, and it looks like you all had transplants and it helps. I can't understand why this isn't working for him. The pills get bigger and smaller, and it's the same tacrolimus? Can anyone tell me if it's the size of the pills?"
- r00...
- July 15, 2013
For Organ Transplant, Rejection Prophylaxis "Renal transplant 2000. No problems besides a slight tremor in my hands. Cyclosporine caused terrible reactions for me, immediately post-transplant. Had to have 6 plasma apheresis rounds to clear the cyclosporine and then smooth sailing on tacrolimus."
Frequently asked questions
- Des...
- Taken for 6 months to 1 year
- July 7, 2023
Tacrolimus for Organ Transplant, Rejection Prophylaxis "My mother is post-op 7 months liver transplant. She was switched to this medication after not tolerating Prograf. The nurse said that this was already FDA approved for kidney and heart transplant patients. But hadn't been approved for liver transplant patients. But they had a very promising trial going with recent liver transplant patients taking Envarsus and having awesome results. My mother was hospitalized for another issue and while she was there she mentioned how Prograf made her feel on a daily basis. They agreed to try her on Envarsus and she has tolerated it better than Prograf. She still experiences some of the same side effects but they are not as bad as when she was on Prograf."
- Ano...
- Taken for 1 to 6 months
- August 25, 2025
"I got prescribed tacrolimus after clindamycin and completely caused a flare-up of my perioral dermatitis. At first, I thought tacrolimus was a gift from the heavens as it literally cleared up my skin by 50% overnight and by 90% in 4 days. After using on and off for about 12 weeks, I noticed that it wasn’t being effective anymore. So I started doing research, and it’s only recommended to be used for 6 weeks and is NOT intended for long-term use. Also, it can cause cancer! My derm never said any of this. Then I noticed how red my face was getting… and I started to get “rosacea-like” redness on my cheeks. I tried talking to my dermatologist about my concerns but was quickly dismissed. Look it up, tacrolimus can induce rosacea. I quit using it, and the redness in my cheeks went away after a few days. Now, I’m in the middle of a very bad perioral dermatitis flare, and I truly believe it’s due to a tacrolimus withdrawal."
- Ken...
- Taken for 1 to 2 years
- February 18, 2021
For Graft Versus Host Disease "The liquid form is sweet! Reminds me of a warm blue popsicle juice. It makes my skin sensitive, and I get nauseous sometimes, but that could be with any of the drugs I'm also on. It is not the worst ever."
- Ano...
- Taken for 1 to 2 years
- June 8, 2025
"Kidney transplant 2 years ago. Was on tacrolimus, which dosage always changes. Got toxic to it. Levels always high. Changed to everolimus but made me ill. Back to tacrolimus 5 mg twice a day, level still too high, then once a day: way too low. Had tremors, brain fog, insomnia. Now changed to Envarsus. Just started. Hope this works. Will be the 4th one."
- Anx...
- January 26, 2013
Tacrolimus for Organ Transplant, Rejection Prophylaxis "Prograf seems, so far, to be a great immunosuppressive medication. Bad - tremors and anxiety."
- Anonymous
- September 24, 2009
Tacrolimus for Organ Transplant, Rejection Prophylaxis "I have been using Prograf for 4 years now. 1 mg in the AM and 1 mg in PM. Last year, or 3rd year into this treatment, I had 2 episodes with squamous cell carcinoma, which were both removed."
- Anonymous
- August 29, 2009
Tacrolimus for Organ Transplant, Rejection Prophylaxis "I take it because I need it. If I did not have a transplant, I would not want to take it because I have gained weight and have edema."
- Anonymous
- August 18, 2008
Tacrolimus for Organ Transplant, Rejection Prophylaxis "I have taken Prograf since my liver transplant eight years ago. Very few side effects. Nothing compared to dying with liver disease. Very blessed from the drug and my donor, Spencer."
- Anonymous
- November 23, 2011
Tacrolimus for Organ Transplant, Rejection Prophylaxis "I'm taking Prograf since 2000. Was seven back then, now I'm 19. Still no side effects, just wanted to check if there are any long-term side effects."
- JJO...
- September 21, 2010
Tacrolimus for Organ Transplant, Rejection Prophylaxis "Liver transplant 8 years ago. No problems."
- ale...
- Taken for 10 years or more
- October 18, 2018
Tacrolimus for Organ Transplant, Rejection Prophylaxis "No problems of liver rejection from when I use Prograf (Tacrolimus), but I have some collateral effects like alopecia and tremors in my hands, and sometimes I feel buzzing in my ears. 9/10!"
- Anonymous
- December 21, 2011
Tacrolimus for Organ Transplant, Rejection Prophylaxis "Started taking Prograf in July of 2011 for my heart transplant. Except for some slight itching and for a little fluid in my ankles, this drug has worked wonders."
- WD4...
- Taken for 6 months to 1 year
- May 24, 2018
Tacrolimus for Organ Transplant, Rejection Prophylaxis "Been using Envarsus XR for over a year. Started at 1.75 mg and now at 1.5 mg. The most notable side effects are the tremors. Hands noticeably shaking. I'm adapting."
- Anonymous
- February 27, 2009
Tacrolimus for Organ Transplant, Rejection Prophylaxis "This has fewer and lesser side effects as compared to other medicines given after organ transplant for my eight-year-old daughter's heart transplant."
- bad...
- April 21, 2009
Tacrolimus for Organ Transplant, Rejection Prophylaxis "I have kidney disease, called IGA nephropathy. I am 14 years old, male, diagnosed in July of 2008. I am finally in remission. I have not yet had a transplant."
- don...
- Taken for 10 years or more
- March 7, 2014
Tacrolimus for Organ Transplant, Rejection Prophylaxis "Easy to take, haven't felt any side effects. No secondary infection. 12.5 years' experience used with CellCept and for a while with Prednisone."
- jdd...
- July 8, 2014
Tacrolimus for Organ Transplant, Rejection Prophylaxis "Some side effects... they've been manageable. Keeping a positive attitude and having a support group has been beneficial."
- Anonymous
- August 28, 2008
Tacrolimus for Organ Transplant, Rejection Prophylaxis "Great drug, it lets me keep my new kidney, but it gives me terrible diarrhea. Just got a kidney 7 weeks ago, had my first one 12 years ago."
- Sen...
- July 7, 2018
For Crohn's Disease "Tacrolimus has too many real side effects. Would the doctor prescribe this to someone they love in their family? I can't believe doctors prescribe this stuff to patients. This stuff is bad. Period."
- del...
- September 4, 2009
For Organ Transplant, Rejection Prophylaxis "Prograf seems to have worked since my liver transplant 4 years ago, but it has also kept me broke, at $1,641 for 60 5 mg caps. I'm grateful to be alive but not happy about what it has cost me."
- web...
- Taken for 1 to 2 years
- August 15, 2021
Tacrolimus for Organ Transplant, Rejection Prophylaxis "Gave me nausea, stomach pain, frequent stool, fatigue, kidney pain. I stopped it and now take only Myfortic and Prednisolone."
- mil...
- Taken for 1 to 6 months
- September 1, 2015
Tacrolimus for Organ Transplant, Rejection Reversal "Standard postoperative organ anti-rejection/immune system suppressant treatment."
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Prograf, Envarsus XR, Astagraf XL, Hecoria
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Prograf, Envarsus XR, Astagraf XL
For Organ Transplant, Rejection Prophylaxis "I’ve been taking Prograf/Tacro for a long time. Maybe started the pill when I was 5 years old? Cyclosporine made me look like an animal-from the pictures I've seen of myself! I’ve had my transplanted liver for just about 28 years, never had any complications. Glory to God! No side effects for me with this medication-taking 1 mg/2x day (both pills at night). That’s not how the meds were prescribed, but I had poor habits as a teen taking this, and the routine stuck. I do not recommend anyone else to follow suit! Haha, just giving my experience. I’m thankful for this medicine!"