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Protopic User Reviews & Ratings (Page 3)

Protopic has an average rating of 7.1 out of 10 from a total of 95 reviews on Drugs.com. 59% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Protopic

Commonly mentioned side effects
  • Tas...
  • January 23, 2018

For Atopic Dermatitis "Using this cream makes my skin as smooth as a baby’s bum. It honestly does work on my eczema, however, I only use it on my face, as I cannot stand the burning sensation. It’s greasy, and so I only use it at night, but the burning hot sensation is not pleasant on the first application. This is why I won’t use it on my arms and legs, as I cannot stand feeling this way. It robs me of my sleep on the first night of application, however, on the second and third day, the burning sensation seems to subside. I tend to spend most of the night sticking my head out of the window to try and catch some cold air. It’s just awful, but it actually works, which is why I persevere."

7 / 10
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  • not...
  • Taken for less than 1 month
  • February 4, 2023

For Atopic Dermatitis "I am a 27-year-old male who suffers from atopic dermatitis. I was prescribed Protopic by my dermatologist to use daily for 2 weeks. The rash on my forehead has worsened, and my face is still red, and my skin is flaky. This has not worked for me."

2 / 10
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  • Jud...
  • May 12, 2017

For Perioral Dermatitis "I've been using Protopic (0.1% ointment) for about six years to treat facial seborrheic dermatitis. On the plus side, Protopic ended five miserable years of itching, redness, and burning that no cream seemed to help, and for that reason, I am truly thankful. On the downside, it's very greasy (similar to Vaseline), which means it stays on the skin all day if applied in the morning. Drinking alcohol is a definite no-no too, as a tiny amount causes an awful reaction, making the skin immediately burn bright red. Annoyingly, if I don't use Protopic for about two weeks, when I reapply it, the skin burns and itches intensely for a few hours (REALLY uncomfortable). Using it more often, say twice a week, does however resolve this problem."

7 / 10
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  • ZBa...
  • Taken for less than 1 month
  • January 12, 2021

For Perioral Dermatitis "Absolutely amazing. Suffered from eczema since I was a year old. Had a flare-up recently on my face, and steroid ointment did not work. Doctor prescribed me Protopic. It burned for a day, but the second day I saw amazing results! Redness, dryness, itching, and burning were gone. On the fourth day, my face is smooth and much calmer. This stuff definitely works."

10 / 10
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7 Report
  • ltm...
  • Taken for less than 1 month
  • November 7, 2021

For Perioral Dermatitis "Used for 3 weeks morning and night to help my perioral dermatitis. Every time I drank even a small glass of wine, the areas I had applied the ointment to began to burn and turned bright red. Even now, 3 days since I’ve used any cream at all, the same reaction occurs. Does anyone know when this will stop happening?! It did clear my skin, but I’m worried the effects were damaging."

7 / 10
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  • Mol...
  • Taken for less than 1 month
  • January 9, 2020

For Atopic Dermatitis "The first time I used this, I only put it around my nose and down to my lip. It burned so bad immediately. I cleaned it off after an hour as the heat and the burning were bad. Even after this, it burned all night, I had to have a fan blowing on me, but that didn't help much. My whole face (not just the area I put it on) burned for over 24 hours, even after washing multiple times. A month later, I tried it again after my skin had calmed a bit, and this time was much better. I didn't get the same burning, just a slight heat from it. Another side effect I've had is that when the room I'm in gets warmer, my whole face burns and gets very red, this lasts for hours. I've been using this for a month now, but I've seen very little improvement with my skin. It's still sore, tight, and burns and itches."

4 / 10
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  • Anonymous
  • Taken for less than 1 month
  • November 22, 2020

For Atopic Dermatitis "I started using this cream on my hands a couple of weeks ago, almost immediately, my hands started burning, but I put it down to the dermatitis. After a few days, there was improvement on my hands, so I carried on using it once a day. Last weekend, I drank wine, and my goodness, my face and neck started burning and went really red. I never correlated it to the cream, I just thought I'd developed an allergy to the wine. That evening, my whole body started tingling, it was quite scary. Still didn't think it could have been the cream, so I carried on using it once a day. The tingling carried on all week, it was driving me to despair. Yesterday, I read the patient leaflet, and to my horror, the common side effects are the ones I was suffering from. I do have sensitive skin, so maybe that's why I reacted so badly. I didn't use the cream last night, still tingling skin today, but not as bad. Hopefully, it will be out of my system soon. My advice is don't use this cream if you have sensitive skin."

3 / 10
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  • Ang...
  • Taken for 1 to 6 months
  • May 21, 2017

For Atopic Dermatitis "Developed eczema on my eyelids and hairline around my face. Itchy, red, and burning for a few months, flare-ups were painful. Dr. prescribed cortisone, but it was only temporary help. I did not apply lots. Then dermatologist prescribed Protopic. Yes, it burned for the first 72 hrs, but it subsided, and I was completely healed within a week! Such a relief. I only apply when I feel like a flare-up is starting. Great for preventing."

9 / 10
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  • Mis...
  • Taken for 1 to 6 months
  • June 19, 2018

For Atopic Dermatitis "This product. -_- I've had eczema for as long as I can remember, and now it's started to spread to new areas. The dermatologist prescribed this to use around the face and neck as it's not a steroid. I was aware that it initially burns the first few times...almost to the point of rather dealing with eczema over the burning. I've used it a handful of times now, as and when. It does soften the thick buildup. However, after applying, the skin is very sensitive to itching. Well...last night I itched my neck 2 hours after applying this...DO NOT DO THIS. I never knew 'burning' had levels 10 times worse than experienced. Had to scrub the area and apply a wet flannel for a good hour to calm it down. It may work, just not for the faint-hearted."

6 / 10
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  • Bro...
  • Taken for less than 1 month
  • June 28, 2020

For Atopic Dermatitis "Patches, newer outbreak of atopic dermatitis not going away with desonide cream. Nasty breakout on right bicep and contact with that side of my body. You can feel and see heavy blotchy lines. Tried Protopic ointment this evening for the first time (Day 1), and yes, I experienced the initial painful itching and burning experienced by so many. I put ice in a baggie directly on the affected areas and instant relief, although it probably dilutes the Protopic strength. I keep on icing as needed. I will do as so many of you recommend and hang in with it for a spell. I'm thinking twice a day until cleared. Thanks so much. I will report back on progress soon."

6 / 10
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  • She...
  • January 4, 2023

For Atopic Dermatitis "It’s only been 5 days, but the itching and burning this stuff caused made me want to rip my skin off. So far, no miracle improvement that others have reported. If anything, the rash looks and feels worse."

1 / 10
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  • Kat...
  • Taken for less than 1 month
  • September 20, 2021

For Atopic Dermatitis "Burning sensation worsened over about 5 days of use. None the first time, then a bit after application, and now a severe delayed reaction (the next day, so I can't just wash it off), nearly constant, and worsened with water. Feels like exposure to jalapenos on sensitive skin, like near the eyes. Hasn't had any effect on my eczema yet either. Can't stick it out to see if it gets better."

1 / 10
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  • Jay...
  • Taken for 5 to 10 years
  • November 14, 2021

For Atopic Dermatitis "Don't bother with Protopic. It works wonders, but you can only use it for 6 weeks. This is what I do, and it works. Overactive immune system, vitamin deficiency, triggers, stress, food allergies. Before food, 3 times a day: vitamin D spray (2000 IU) per spray, 6 sprays a day (12000 IU), lower when symptoms improve to (6000 IU) daily. CBD full spectrum spray, 6 sprays a day (800 mg). MCT oil as a base (normal function of immune system). Multivitamins. Dead Sea salt bath, shower off salt water after bath."

5 / 10
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  • Mr ...
  • May 18, 2017

For Atopic Dermatitis "I had a rash caused by insect bites, so the doctor gave me Protopic. He said it would get rid of the rash. I had tried everything: calamine lotion, baking soda, tea tree gel with vitamin E, lavender, rosemary oil, and witch hazel. Well, nothing got rid of the rash, also, my skin cannot handle hydrocortisone cream, and I cannot take Benadryl. So I got the Protopic and antibiotics. Yes, it cleared it away brilliantly, however, the doctor told me to use it twice a day, incorrect dosage. Did not warn me of evil side effects. My skin became a mess as soon as I stopped using it, remembering the doctor saying to apply more if I had any problems. It would clear my skin, then get worse and worse: leathery skin, painful blisters, oozing nasty redness, bumpy skin - Red Skin Syndrome."

1 / 10
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  • qrk...
  • Taken for less than 1 month
  • October 21, 2017

For Atopic Dermatitis "Applied this to treat what looked like a mix of folliculitis and atopic dermatitis flares (but which turned out to be just atopic dermatitis) on both lower legs, especially the shins. Itchiness, redness, and dryness abated about 80% after one week without any initial irritations or burning sensation. There is no feeling of soreness or increased sensibility whatsoever, I've basically just stopped thinking about those problematic parts of my skin, so there's that passive psychological boost, too. Only 9/10 because long-term results are still unknown and because it's pretty greasy."

9 / 10
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  • Arc...
  • Taken for 1 to 2 years
  • January 4, 2022

For Atopic Dermatitis "Like rubbing lava on my skin, makes me feel like I'm on fire, makes my skin redder and worse. Increases my stress levels, causing me to scratch more. The worst thing I have ever been prescribed for this condition."

1 / 10
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  • tak...
  • Taken for 6 months to 1 year
  • July 23, 2022

For Atopic Dermatitis "Dermatologist prescribed for facial dermatitis. After some time, warts appeared due to lack of immunity. Please take caution, I have warts now for over 3 months. Remedy is to allow the immunity to redevelop over months and then with nitrogen removal. A very unpleasant experience."

2 / 10
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  • Blo...
  • Taken for less than 1 month
  • June 23, 2022

For Atopic Dermatitis "I went camping over Memorial Day at our ranch... Long story short, it's Oklahoma, it's summer, IT'S CHIGGER TIME! Got torn up on my genitals. After an appointment at Urgent Care and a negative STD test for herpes, the clap, syphilis, etc., the doctor gave me some antibiotics (Cephalexin 500mg x 4 daily & Hydroxyzine). After 4 days, all looked promising, ran out of antibiotics... All resumed. After 3 days of swearing I would castrate myself just to stop the itch... Went to a dermatologist. Same tests for STDs all over again, but was given more antibiotics and 0.1% Protopic. Put on at 12:05 pm after picking up from the pharmacy. About 7:00 pm my penis was burning."

1 / 10
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  • Wen...
  • Taken for less than 1 month
  • December 23, 2023

"I developed contact dermatitis on both eyelids out of the blue (unidentified trigger). Both eyelids were badly inflamed with infuriatingly itchy and sore red patches of skin, both on upper eyelids and the lower ones, with some swelling. Having tried absolutely everything, including hydrocortisone cream, all with zero effect, my doctor advised I tried 0.1% Protopic. Feeling nervous about possible side effects, I was willing to try anything that might help. For the first 2 days, I had dreadful side effects of itching at an intensity I hadn’t believed would be possible, stinging, and burning. Having read that the side effects ease after several days, I persevered, but it was truly shocking. I am so glad I did. By day 3, my eyelids were vastly improved, and the severity of the side effects greatly reduced (none by day 4). By day 6 (today), my eyelids are completely recovered. Seeing my doctor in 2 days to discuss weaning off Protopic. Don’t be scared to give it a try and a chance to work."

10 / 10
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  • Tin...
  • Taken for 1 to 6 months
  • September 18, 2021

For Atopic Dermatitis "Literally saved my life. Before: my whole face was covered in dry, itchy, red, painful eczema - I could barely open my eyes or move my mouth. It was horrible. Went to my dermatologist; within one week, it almost completely cleared up - I saw daily improvements. It was amazing. I love it so much!! I haven't had a flare-up in months. I don't use it on a daily basis, only to treat mild red patches at times. Very good for prevention. No side effects for me. It's gentle and loving."

10 / 10
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  • Pat...
  • Taken for 10 years or more
  • December 29, 2021

"Incredibly effective for my psoriasis, no burning, a little goes a long way. I've been using it for ~23 years, with ZERO noticeable adverse side effects. My profound gratitude to the Japanese chemist who developed tacrolimus (generic name for Protopic)."

10 / 10
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  • Gra...
  • Taken for less than 1 month
  • April 26, 2023

For Perioral Dermatitis "This stuff was amazing for my child. The doctor first recommended Polysporin, but it did nothing. The next recommendation was Protopic, and within three days of applying it twice a day as instructed, the dermatitis was almost gone."

10 / 10
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  • Ste...
  • March 28, 2018

For Perioral Dermatitis "I had a very bad experience after applying the Protopic ointment on my cheeks and chin two times only. I paid $92.00 for a tube of 30g and can't use it because I got a huge burning sensation all over my face for 3 days and 3 nights. I had to sleep with an ice pack on my face and hold ice during the day. It looks like I was allergic to it, and the horrible pharmacy in Vancouver, BC would not give me my money back. I would never recommend this medication to anybody!!! I went to see my other clinic doctor, who said that Protopic tacrolimus 0.1% ointment is very strong. He gave me a mild compounded cream instead. I lost the money on Protopic 0.1% ointment and had to pay for my new cream again. Unbelievable...."

1 / 10
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  • Kon...
  • Taken for 6 months to 1 year
  • May 20, 2018

For Perioral Dermatitis "I'm using this to prevent pityriasis alba as a result of eczema. Protopic is very greasy, so I use it at night only, and only on affected spots every few days (when needed). It takes away all signs of my eczema within a few days, and I haven't had a single spot of pityriasis alba since using it. I haven't noticed any side effects or burning. Corticosteroids had no impact on my eczema whatsoever. Love this product."

10 / 10
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  • d61...
  • Taken for less than 1 month
  • March 31, 2022

For Atopic Dermatitis "2/4/22 I woke up to red, swollen eyes. I went to my primary care doctor, who prescribed prednisone. The medication made the swelling go away. When I was done with the steroids, the swelling would immediately come back. I was on 3 rounds of steroids, including a steroid shot. My doctor could not determine the cause of the swelling. I was sent to see a dermatologist, rheumatologist, and allergist. All of my blood work came back negative for an autoimmune disease (they thought the swelling was possibly lupus). The allergist finally prescribed Protopic last week. It was very expensive, not covered by insurance, but I was willing to try anything. I needed to get off steroids since I had been on them since February. I started the Protopic Tuesday, and this is Thursday, and my eyes look like they are improving. When I apply the ointment, it does burn and itch, but it is manageable for me. If it helps stop the swelling and I don't have to miss work, then I will deal with the minor side effect."

8 / 10
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