Skip to main content

Tacrolimus topical for Atopic Dermatitis User Reviews (Page 3)

Brand names: Protopic, Tacrus

Tacrolimus topical has an average rating of 6.4 out of 10 from a total of 112 reviews for the treatment of Atopic Dermatitis. 54% of reviewers reported a positive experience, while 31% reported a negative experience.

Reviews for Tacrolimus topical

  • Tas
  • January 23, 2018

Protopic (tacrolimus) "Using this cream makes my skin as smooth as a baby’s bum. It honestly does work on my eczema however I only use it on my face as I cannot stand the burning sensation It’s greasy and so I only use it at night but the burning hot sensation is not pleasant on the first application This is why I won’t use it on my arms and legs as I cannot stand feeling this way. It robs me of my sleep on the first night of application however second and third day the burning sensation seems to subside I tend to spend most the night sticking my head out of the window to try and catch some cold air. It’s just awful but it actually works which is why I persevere"

7 / 10
Was this helpful?YesNo
11 Report
  • Anonymous
  • December 20, 2020

Protopic (tacrolimus) "This definitely works, but you must stick with it! When I first put it on my skin (face and neck only), it felt extremely hot and very, VERY itchy. I thought I was having an allergic reaction to it and/or my skin flare up was getting worse. After several hours the itching dissipated and my skin just felt hot in the worst affected areas - this wasn’t too bad at all. The redness also cleared up and my skin started looking totally normal (as if I didn’t have eczema). Pretty amazing result."

9 / 10
Was this helpful?YesNo
7 Report
  • life...
  • Taken for 1 to 6 months
  • January 27, 2024

Protopic (tacrolimus) "A 45-year-old woman who has chronic eczema flares on my face, neck, and eyes worsening with perimenopause. I have used steroid cream historically on my body, but not on my face. I developed steroid-induced acne rosacea, followed by daily flares. Eventually, I was referred to a dermatologist who prescribed Protopic 0.03% to use daily on my face and neck. Having read reviews, I expected to be in agony, but apart from a slight flushing (nothing like the pain of a flare), within days my flares had subsided. I'm 6 weeks into using it and my life has changed for the better. I can now wear makeup that I never used to, even some perfumes. My skin looks clearer - I've never seen it so well-controlled. I hope this works for you because I've tried everything before this, including 3 months on antibiotics (oxytetracycline, lymecycline), which made me itch all over. I used to take antihistamines (fexofenadine) daily, so that I couldn't prevent flares. Now, I don't need to take them."

10 / 10
Was this helpful?YesNo
1 Report
  • Ang
  • Taken for 1 to 6 months
  • May 21, 2017

Protopic (tacrolimus) "Developed eczema on my eye lids and hair line around my face. Itchy red and burning for a few months flare ups were painful. Dr prescribed cortisone but it was only temporary help. I did not to apply lots. Then dermatologist prescribed protopic. Yes, it burned for the first 72 hrs but it subsided and I was completely healed within a week! Such a relief. I only apply when I feel like a flare up is starting. Great for preventing."

9 / 10
Was this helpful?YesNo
11 Report
  • not...
  • Taken for less than 1 month
  • February 4, 2023

Protopic (tacrolimus) "I am a 27-year-old male who suffers from Atopic Dermatitis. I was prescribed Protopic by my dermatologist to use daily for 2 weeks. The rash on my forehead has worsened and my face is still red and my skin is flaky. This has not worked for me."

2 / 10
Was this helpful?YesNo
3 Report

Are you taking this medicine?

  • Shel
  • January 4, 2023

Protopic (tacrolimus) "It’s only been 5 days-but the itching and burning this stuff caused made me want to rip my skin off. So far no miracle improvement that others have reported. If anything the rash looks and feels worse"

1 / 10
Was this helpful?YesNo
3 Report
  • Mr Xl...
  • May 18, 2017

Protopic (tacrolimus) "I had a rash caused by insect bites so Doctor gave me Protopic he said it would get rid of rash. I had tried everything : calamine lotion, baking soda, tea tree gel with vitamin E, lavender rosemary oil & with hazel, well nothing got rid of rash also my skin cannot handle hydrocortisone cream & I cannot take benadryl. So I got the protopic & antibiotics. Yes it cleared it away brilliantly, however Doctor told me to use twice a day incorrect dosage. Did not warn me of evil side effects. My skin became mess soon as I stopped using remembering Doctor saying apply more if you had any problems, it would clear skin then get worse and worse leathery skin painful blisters ozzing nasty redness bumpy skin - Red Skin Syndrome."

1 / 10
Was this helpful?YesNo
10 Report
  • Brock...
  • Taken for less than 1 month
  • June 28, 2020

Protopic (tacrolimus) "Patches, newer outbreak of atopic dermatitis not going away with desonide cream. Nasty breakout on right bicep and contact with that side of my body. You can feel and see heavy blotchy lines. Tried Protopic oinment this evening for the first time (Day 1), and yes I experienced the initial painful itching and burning experienced by so many. I put ice in a baggie directly on the affected areas and instant relief, although it probably dilutes the Protopic strength. I keep on icing as needed. I will do as so many of you recommend and hang in with it for a spell. I'm thinking twice a day until cleared. Thanks so much. I will report back on progress soon.- Brock"

Was this helpful?YesNo
6 Report
  • Anonymous
  • Taken for less than 1 month
  • February 25, 2021

"Definitely helps reduce some of the flaking skin around my eyes but when I used it it made my eyes feel very hot like I put my eyes next to a heater. Tried washing my face and the hotness still didn’t go away. It’s been almost 24 hours now and I can still feel it on my eyes. It’s not horrible by any means but I will probably not use this again unfortunately I don’t want the hotness getting any worse."

4 / 10
Was this helpful?YesNo
5 Report
  • Kano
  • July 29, 2019

"I can't say this ointment failed to clear up the rash around my eyes. Unfortunately, the side effect is worse, because the rash began appearing all over my face. When I use a simple cortisone cream, the rash just disappears. I have tried more than once with Tacrolimus, but it seems to spread the rash as it works. So no, I am not satisfied with this product. Has anyone else experienced this?"

3 / 10
Was this helpful?YesNo
7 Report
  • Kate
  • Taken for less than 1 month
  • September 20, 2021

Protopic (tacrolimus) "Burning sensation worsened over about 5 days of use. None the first time, then a bit after application, and now a severe delayed reaction (the next day, so I can't just wash it off), nearly constant, and worsened with water. Feels like exposure to jalapenos on sensitive skin like near the eyes. Hasn't had any effect on my eczema yet either. Can't stick it out to see if it gets better."

1 / 10
Was this helpful?YesNo
4 Report
  • itchy...
  • April 25, 2013

"I was prescribed Protopic for atopic dermatitis on my eyelids, which had been kicking around my eyelids for about 4 months, really irritating. The first application definitely was on the hot/burning side for about 12 hours, the second and third applications were not. The Atopic dermatitis appears to be improving. Also, I do not know if it was coincidental, but I woke up at 4AM with a heavy migraine and then got sick, that may have been from the meal I ate at 9PM, some sort of food poisoning, because I had gas all day long and the food did all come up. Don't know, but I am fine 24 hours later."

5 / 10
Was this helpful?YesNo
11 Report
  • staylor
  • April 25, 2016

"I have suffered like many others for years with rubbish skin. Had every steriod under the sun but wanted to try and stop the problem from happening in the first place. I was prescribed Protopic. Yes, at first it burns like hell, but that to me is it working and I suffer it. As I continue to use it this burning doesn't happen and it has left me with lovely skin. I have found however that I did not apply on the Thursday and had some alcohol on the Friday thinking the cream would be out of my system, but definately not! My face became very flushed when I started drinking but then calmed down. My eyelids and area around the eye was completely swollen the following morning and has just got worse....will need to monitor this."

9 / 10
Was this helpful?YesNo
8 Report
  • qrk
  • Taken for less than 1 month
  • October 21, 2017

Protopic (tacrolimus) "Applied this to treat what looked like a mix of folliculitis and atopic dermatitis flares (but which turned out to be just atopic dermatitis) on both lower legs, especially the shins. Itchiness, redness and dryness abated about 80% after one week without any initial irritations or burning sensation. There is no feeling of soreness or increased sensibility whatsoever, I've basically just stopped thinking about those problematic parts of my skin, so there's that passive psychological boost, too. Only 9/10 because long term results are still unknown and because it's pretty greasy."

9 / 10
Was this helpful?YesNo
7 Report
  • OnceT...
  • Taken for less than 1 month
  • February 22, 2017

"I think I was suffering from topical steroid withdrawal, and tried to get off of them once my skin was dry, red, and flaky. I thought I was out of options until I remembered the Protopic generic, tacrolimus. I asked my doctor about it, and she was able to prescribe it to me. So far, it's cleared up my skin, although I do I have red skin on my thighs. I get itchy and keep causing more eczema or sores due to scratching, and I'm unaware of the allergens causing it. It does burn, and I'm odd, I think it feels good sometimes, especially in the winter. I recommend it for eczema sufferers, because I've used it in the past, and it's worked, and as an adult now, it's working again for me. Topical steroids have failed me."

8 / 10
Was this helpful?YesNo
7 Report
  • Archie
  • Taken for 1 to 2 years
  • January 4, 2022

Protopic (tacrolimus) "Like rubbing lava on my skin, makes me feel like I'm on fire, makes my skin redder and worse. Increases my stress levels causing me to scratch more. The worst thing I have ever been prescribed for this condition."

1 / 10
Was this helpful?YesNo
3 Report
  • Chris...
  • Taken for less than 1 month
  • September 26, 2019

"I have had eczema for a couple months now and nothing has made my confidence go down as much as eczema has. Being uncomfortable in your own skin and not being able to hide it even when you wear makeup sucks. HEAR ME OUT: I have used Eucrisa before this religiously, no it did not seem to help the eczema go away, but it helped the redness go down. I was nervous to try Tacrolimus because of all the reviews but I decided to give it a try so I could gain my confidence back. I started off by just putting a little bit on a small area of my eczema. I HIGHLY recommend doing that. Its only been 4 days since I have used it and I am one of the few that has had little to no side effects and about 50% of my eczema is gone. Please be aware that everyone's experience will be different. I also recommend putting a base layer of moisturizer on before applying the cream. For me, this cram has been a miracle and I hope everyone finds something that works for them."

9 / 10
Was this helpful?YesNo
5 Report
  • Marth...
  • February 5, 2017

"My Dr. prescribed this ointment in conjunction with memetisone cream. I had a severe reaction with red, hot, weepy, itchy, thin feeling skin that bleed with lightest scratch. Per Dr. I stopped using memetisone and just used tacrolimus, from there skin dried up and became very scaley, still itchy, thin feeling and painful. The ointment also made my skin feel vey dry."

3 / 10
Was this helpful?YesNo
7 Report
  • kdub
  • January 14, 2019

"I've had eczema for my entire life but it started getting really bad around my eyes in the last year. It was super dry and flaky and nothing seemed to work. I tried tacrolimus and the first night I put it on it burned and itched so bad. When I woke up the next morning it was still mildly burning but after two more uses all symptoms stopped and my eczema began to clear. My face was clear within 5 uses but I continue to use it every night. This ointment isn't any gooier than steroid cremes I have been prescribed and it actually works."

8 / 10
Was this helpful?YesNo
5 Report
  • Ani
  • September 19, 2018

"Few days back I had been to my dermatologist they recommended me tacrolimus ointment to apply on the affected spots on my face and from where I remembered it itched so bad I didn't have any burning sensation though but the itching was too severe and my face was getting light reddish too. I thought that it had some kind of allergic reaction with my skin ...but only in 2 days the white spots started vanishing and the itchiness subsided after 5 days and in 1 week I got a clear smooth skin. It really did work (though it needs a lot of patience about the greasiness and for the annoying itching but it really does work)"

9 / 10
Was this helpful?YesNo
5 Report
  • Eczema...
  • Taken for 1 to 6 months
  • March 17, 2021

"After 19 solid months of awful flare ups after being relatively flare free for close to 25 years, my internist finally prescribed generic protopic (tacrolimus). After the first evening, in which I felt like my face was on fire and kept waiting for family to ask why is your face so red?” (they never did, apparently it was just feeling hot not looking it), it has been wonderful. If you can make it past the first 5 hours, it’s a breeze and it helps a lot. I am a new person and coworkers have said my skin is “glowing”!"

9 / 10
Was this helpful?YesNo
3 Report
  • Blowt...
  • Taken for less than 1 month
  • June 23, 2022

Protopic (tacrolimus) "I went camping over memorial day at our Ranch... Long story short, its Oklahoma its summer, IT'S CHIGGER TIME! Got torn up on my genitals. After an appt at Urgent Care and a negative STD test for herpes, the clap, syphillis, etc. The doc gave me some antibiotics (Cephlaxen 500mg x 4 daily & Hydroxyzine). After 4 days all looked promising, ran out of antibiotics... All resumed. After 3 days of swearing I would castrate myself just to stop the itch ... Went to a dermatologist. Same tests for STD's all over again, but was given more antibiotics and 0.1% Protopic. Put on at 1205pm after picking up from pharmacy. About 1900 my penis was burning"

1 / 10
Was this helpful?YesNo
2 Report
  • Georgia...
  • Taken for 1 to 6 months
  • March 6, 2019

"What a waste of money. I used the first tube of Tacrolimus 0.1% and saw no results of my bumps and awful itching. Well, I thought the medication took a while to work and I am not almost through my second tube and it still doesn't work Each tube cost me $129 and that was only the part I paid, insurance paid the most. It is a worthless drug for me. I still crazy itch. Don't waste your money. Over the counter hydrocortisone works as well at a fraction of the price and it's not as super greasy as Tacrolimis. I am so disappointed,"

1 / 10
Was this helpful?YesNo
4 Report
  • AVano
  • Taken for less than 1 month
  • January 22, 2019

"I've been dealing with perioral dermatis and eczema on may face since June 2018. My face blew up after topical steroids were applied for what I thought was eczema. Fast forward to now Jan 21 2019 my skin I literally clear. I tried EVERYTHING. I spent sooo much money. I did take a round of prednisone in August and that help a lot but I was still getting these crazy flares. This ointment has been a life changer. It does burn and sometimes its for the first 2 application....but trust me it will get better. This is the first time in over 6 months that I have been rash and itch free. I also use Specto gel face soap."

10 / 10
Was this helpful?YesNo
4 Report
  • Ann
  • Taken for less than 1 month
  • October 17, 2020

"Well, most of the comments on here are written by lucky lucky people. It didn’t “cured” me in 2 days. I’m 2 weeks in and there is only a tiny little bit of positive change on ONE of my 16 patches (and it’s ON MY FACE. so I was very hopeful) Lucky you if it works in 2 days- if it’s true I totally envy you. It does itch and burn the first few days but you’ll get through it. My skin felt very hot as well even after 10 hours and more from the application. It’s still itch a bit now; it made some of my patch very red and raw. I almost gave up a few times but will continue to use it twice a day until I have my skin biopsy result in 10 days. Oh and if you are in Canada and don’t have insurance, this product cost around a 100$ (a heads up is always good. Especially when spending that much money for something that doesn’t work in 2 days like all of these people said)"

1 / 10
Was this helpful?YesNo
3 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Atopic Dermatitis

Care guides

Symptoms and treatments

Medicine.com guides (external)