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Bactrim DS and Tiredness: What Users Say (Page 2)

Reviews for Bactrim DS

Commonly mentioned side effects
  • Abb...
  • Taken for less than 1 month
  • May 30, 2019

For Bacterial Skin Infection "I developed a painful staph infection in my nose after a really nasty cold. Bactrim DS cleared it up quickly, but it was harsh on my body. The worst side effect that I had was extreme fatigue. Even walking around the house left me dizzy, out of breath, and shaking with exhaustion. Luckily, I had the sick days to take off work because I don't think I could have done it. I also had nausea and insomnia, but that was mostly just inconvenient. The exhaustion, though, was debilitating. I finished the entire 10-course because the staph infection was painful, and my nose was bright red and swollen. I was scared not to finish the meds. I would definitely ask for something else next time, though."

2 / 10
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  • Nub...
  • December 14, 2017

For Urinary Tract Infection "Horrible! I will tell you it does work for a UTI. My UTI is almost gone, but the side effects are terrible. I was doing fine with the medication the first day, and now today is my second day. Currently, I am at work, jittery, having chills, I had two panic attacks, and today I just started having migraines. I am only on this for three days. I have two more pills left. Tried to make it, but I don't think I can handle this while working. Not so much dizziness for me, just making me really tired. I will be staying on Cephalexin."

2 / 10
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  • Kat...
  • Taken for less than 1 month
  • March 8, 2021

For Bacterial Skin Infection "Been on Bactrim DS due to a skin infection after surgery. I take 2 a day, 12 hours apart. It is helping a whole lot, but I am so tired and weak. When I eat, it makes me want to vomit. Will be so glad when the script is gone!"

6 / 10
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Frequently asked questions

  • Jam...
  • Taken for less than 1 month
  • August 4, 2021

For Bacterial Skin Infection "Male, 49 years of age. Took Bactrim DS 2x a day for 14 days. I took it for an infected boil on my back. Within 2 days, the boil began shrinking and the infection began clearing up. Side effects for me were exhaustion and muscle weakness. During the second week, I would become tired to the point of falling asleep just from taking a shower and getting dressed. My arms were so weak I could hardly lift a bag of groceries (I can bench 200 lbs). My legs were sore like I ran a marathon. All of this cleared up about 3 or 4 days after I finished taking them. Overall, it was worth it for me."

8 / 10
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  • RGa...
  • Taken for less than 1 month
  • January 8, 2021

For Urinary Tract Infection "Awful!! Had a 5-day/10-pill prescription of Bactrim for a UTI. Just thought I was lethargic the first day, but later that night my hands were shaking, heart beating fast, which induced a full anxiety attack. Kept taking the pills. Fast forward to day 4 and my head was so foggy I felt like I was a walking zombie, and the shakes got so bad I had to go to urgent care. No appetite whatsoever. Cleared up the UTI but avoid at all costs!!"

2 / 10
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  • Anonymous
  • December 31, 2016

For Prevention of Bladder infection "I was having symptoms of a UTI for a few weeks, so I finally went to the ER when the pain got worse. They gave me Bactrim. Two days after taking it (twice a day), I got flu symptoms/a cold. Today is my fifth day on it, and I feel awful, shortness of breath, so, so tired, and I feel so nauseous. And I'm still having pain when I use the bathroom, so I don't even think it's working. Going to call the doctor tomorrow, I won't be continuing this medicine."

3 / 10
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  • Mar...
  • Taken for less than 1 month
  • April 29, 2017

For Urinary Tract Infection "Prostate UTI asked not to be given Cipro as it can cause permanent tendon damage if you are doing repetitive movements. See CBC news article. They gave Bactrim. It's a poor substitute. Dizzy, tired, dry eyes, damn slow working. On day 4 of 7, not much better. Cipro is the one of choice for prostate in my experience to work well, but it has its side effects too."

6 / 10
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  • FIR...
  • Taken for less than 1 month
  • August 16, 2024

For Kidney Infections "I am not a huge fan of how I feel while on it. I have had significant constipation, a slight headache, and some slight lightheadedness. A little bit of tiredness. I also don't like how large the pills are. Other than that, though, I have tolerated it well. I have been drinking so much water (10+ glasses) a day on it too. Does not seem to upset my stomach (other than the constipation discomfort). I do fear, though, that it is not knocking out my kidney infection as I am still having some symptoms while on it for 10 days."

8 / 10
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  • Cat...
  • Taken for less than 1 month
  • July 11, 2022

For Urinary Tract Infection "I am generally very sensitive to medications, and antibiotics usually make me feel awful. I had never had Bactrim DS before, and I've had reactions to several other antibiotics in the past, some just unpleasant, some possibly life-threatening-unpleasant to life-threatening. I research everything before I take it, and I had some serious anxiety after reading some of the reviews here. With the 1st day's doses, I ate a full meal, drank tons of water (which I was doing anyway), took probiotics between doses, and braced myself for the worst. I was tired for a couple of days and very mildly nauseous, but that was it. By the last dose (5-day course), I was only eating a small snack with it and no nausea at all. Unfortunately, it didn't cure the UTI. Symptoms did improve for a while. Doc is culturing urine now and put me on Macrobid until we know. Hoping for another easy ride with that. Feel better, everyone!"

7 / 10
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  • Anonymous
  • February 18, 2009

For Bacterial Skin Infection "It makes me quite tired and somewhat confused."

4 / 10
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  • Net...
  • Taken for less than 1 month
  • December 18, 2015

For Bacterial Infection "I was prescribed Bactrim DS for folliculitis. It did nothing except make me tired and gave me a yeast infection. Trying Keflex now and hoping for better results."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.