Mirapex for Restless Legs Syndrome User Reviews (Page 2)

• Mam...
• Taken for 10 years or more
• June 21, 2017

"I have had RLS for nearly 10 years. I have taken Requip, which didn't do anything. Now I take Mirapex. I started out on 0.125, which did nothing. I moved up to 0.5 mg and have taken that dose for about 9 years. Now, my legs and sometimes my arms go crazy on me during the day. I can't ride very long in a car because it drives me insane how my legs feel. I get very frustrated fast and become agitated. I often tell my husband I would rather cut my legs off than feel this way. I went to the doctor today, he moved my dose to 1 mg. I pray this will help me. I am also suffering from compulsive gambling and weight gain of 25 plus pounds. We need a cure for this horrible disease!!!"

• Meg...
• Taken for 10 years or more
• August 23, 2016

"While my RLS inevitably was in the evening, I also had it during the day. My dose slowly increased to 1 mg three times a day. Two years ago, I fell asleep while driving, then later I was told I was 'napping' for seconds to 10+ minutes even while conversing. Last month, typing at the table, I 'found myself' standing over my chair reading something I had not typed, and was frightened! Then, I was working in my kitchen -- then was in another room about to sit down, landing hard on the kitchen floor. Have tried 2 newer meds with no RLS relief. Now decreasing Mirapex, take 0.5 tid (half previous dose), and today trying twice daily. My neurologist is trying alternative meds, and so far nothing works but pramipexole, so I am decreasing the dose every few days."

• Wor...
• April 7, 2008

"In the past, I took Mirapex for moderate-to-severe Restless Legs Syndrome. It was 100% effective in eliminating all symptoms. I had no side effects. I currently take REQUIP which is also 100% effective. I switched to Requip to take a drug holiday from Mirapex, upon the recommendation of my neurologist."

• Cat...
• November 14, 2015

"I rated this based on how the medicine worked in the beginning. However, over time my symptoms became worse, would happen during the day, and I had to take the medication around 6 pm to be effective by 10 pm. I am now on a low dose of Tylenol 3 that I take 30 minutes before bed. In the three months I have been on this regimen, my daytime symptoms have disappeared. I have not had to increase dosage or felt the need to take the medicine at bedtime (major concern of doctors is becoming addicted to anything with codeine/opiate). Also tried gabapentin. It was a nightmare."

• thi...
• Taken for 1 to 6 months
• March 14, 2013

"I started getting Restless Legs Syndrome in 2010, it caught me off guard. I was taking Requip, and that worked for a while, but I found that I was getting leg shaking during the day. Since I sit at a computer all day, this was very annoying and would actually interfere with my job. So I started taking the Requip during the day to alleviate the shaking, that made me very tired. I went to a neurologist, and he changed my script to Mirapex. The first night was wonderful, the next full day, I was sleepy. He had put me on 0.5 tabs 3 times a day. I found that if I cut a tab into quarters, I could take 1/4 during the day with minimal sleepiness, and 1/2 tab at night when I wanted to sleep really well. So I ended up taking the pill just 2 times a day."

• rob...
• June 29, 2017

"I was on Mirapex for RLS for about 11 years. At first it got much worse. I had uncontrolled arm and leg movement when relaxed or sleeping. I did not get sleep. Finally went to a neurologist. He started me on 300 mg of Gabapentin and worked up to 1200 mg at night and 300 mg in the morning and afternoon. Then I started to reduce Mirapex. I went through severe withdrawal for 5 days and moderate for another 5 days. I now can sleep and the uncontrolled movement is minimal. My neurologist said that Mirapex was the cause of my worsening condition."

• Bea...
• Taken for less than 1 month
• October 6, 2017

"I have had RLS for years. I dealt with it for a long while until it started doing it during the day and started creeping into my arms. Got put on Mirapex to attempt to control it. It was the most awful thing I've ever taken. Lost huge chunks of memory, couldn't keep up with conversations, hallucinations, and major insomnia. I couldn't sleep before, but to be given a 'wonder drug' and have it exacerbate the situation was beyond bearable. No thanks."

• wad...
• June 1, 2010

"For nearly ten years, I struggled with restless leg syndrome, a truly miserable and frustrating condition. The only 'treatment' I found to be effective was to get up and walk about. However, between about midnight and 6:00 a.m., this becomes quite inconvenient. Soaking in water as hot as I could stand worked only for a few seconds. Relief from massages was also extremely temporary. Initially, I tried Requip, which seemed like it might be helping a teeny bit, but left much to be desired. Later, a neurologist switched me to Mirapex. Following a 'breaking in' period, at long last, I found relief from this miserable condition. As long as I take my daily doses, I have relief. So far, so good."

• jac...
• October 31, 2010

"I did not develop RLS until my early 70s. Began with 0.5 mg Mirapex once daily, went to twice daily (same dosage), then finally to 1 mg twice daily, been on it for a year now and is working fine. Tell you what though, DON'T let your script run out and have to wait. You won't like it! It's like going off something 'cold turkey'. I did once and had to wait for 4 days. Very unpleasant experience."

• old...
• Taken for 10 years or more
• August 13, 2012

"Mirapex (Pramipexole) is truly a wonder, it takes away 99% of my symptoms if taken early evening. I've used it for 10 years or more now, and it hasn't failed me until lately, as my dose is now at 1 mg at night and 0.5 mg in the morning. My symptoms do come up early enough to get me out of bed in the morning once in a rare while."

• Anonymous
• September 20, 2008

"Mirapex has worked like a miracle for me. I can go on long trips again without constant leg 'stretching/wiggling/massaging/exercising/deep-knee-bending' to take away the terrible sensations in my legs! I also do not 'twitch' and 'kick' in bed, like I used to."

• Anonymous
• February 29, 2012

"This somewhat reduced my restless legs syndrome (which occurs every other day and is enough to keep me up at night and be bothersome); however, this gave me insomnia, specifically causing me trouble falling asleep, and once I was finally able to fall asleep, I would wake up once every two hours or so."

• wig...
• Taken for 5 to 10 years
• December 29, 2014

"This has been extremely useful in stopping my restless legs at night. If I happen to stop or run out, I'm experiencing the restless legs again. I hate that feeling and have to get up and shake my legs. It is a feeling I simply can't stand!"

• vel...
• Taken for 5 to 10 years
• June 24, 2012

"I have been taking Mirapex for 7 or 8 years, I am now up to 0.50 to 0.75. It has worked well for me, except I have gained a lot of weight, and now I am having augmentation, meaning my legs start jerking earlier in the day and my arms are starting to have it. I can't increase it much more, too much fatigue. I am concerned about what I am going to take now. I've tried other things that don't work, so beware of dopamine agonists. After so many years, you become immune to it, unfortunately. I could not afford it if I had not qualified for the patient assistance program, I don't have insurance."

• Lit...
• Taken for 1 to 6 months
• July 30, 2016

"I have had RLS for years, but since going off clonazepam 1 year ago, it increased so severely afternoon, evening, and night that I was going crazy. Pramipexole at 2mg finally stopped it. I tried other meds and all suggestions I could find on the Internet. For about 2 months, I have been taking iron, more magnesium with my calcium, folic acid, a good multi, and hope it is helping. The pramipexole has been a lifesaver. I do not have insurance, but I get my meds at Universal Drugstore, an online drugstore in Canada. The pramipexole comes from the UK and is really cheap compared to all the prices elsewhere."

• Cat...
• Taken for 10 years or more
• June 17, 2017

"I have tried most of them. Mirapex works well, and I have had no side effects. I tried to stop all my meds that I've taken - some for 40 years - so I could see how bad the condition had become over 40 years. It was terrible, I can't imagine surviving life had Mirapex, Sinemet, and Clonopin not come along. Opioids work well too. Cannabis helps a lot."

• lon...
• September 20, 2011

"Severe restless legs syndrome with periodic limb movement for over 45 yrs. Clonazepam worked fine for a long time, then became less effective. Doctor added Mirapex - it worked BUT: I gained 60 lbs in 3 yrs from obsessive eating, charged a lot of money to my credit cards due to obsessive spending (both stated side effects), AND fell asleep without warning, mostly at night (twice while driving), so I tapered off. Have lost most of the weight, paying off the bills, but need more than clonazepam."

• Old...
• December 28, 2015

"On Requip several years when it stopped working. Switched to Mirapex 1 mg and had immediate relief. Now, 6 months later, RLS back for 3 to 4 hours at bedtime. Also, some symptoms during the day, so sometimes take 0.5 mg during the day with some relief. No significant side effects."

• Ano...
• March 13, 2009

"I take half a pill around supper time so I can sleep. My restless leg syndrome usually kicks up right before bed. I wouldn't be able to sleep without it. It has been wonderful to just go to bed and really rest."

• Bub...
• April 18, 2015

"Have had RLS since I was 10 years old (now 62 yrs old). In my 20's, RLS really started causing me problems. I have had different types of medications, dosages, and combinations. My doctor put me on 0.5 mg Mirapex three times a day. Usually only take it twice, afternoon and bedtime, unless I am having a bad day of RLS. Mirapex has been fantastic for me. If I am very active during the day, I take a pill in the morning. Never experienced side effects. Some evenings the RLS stays active, I get up, take a 15-minute hot bath, back to bed. This seems to resolve this problem. Every nerve in my body now becomes unnerved for about 5 to 30 minutes after taking Mirapex. My neurologist said the RLS is a problem since I have had RLS for over 50 years."

• Bos...
• Taken for less than 1 month
• January 31, 2015

"I'm writing from the UK! The main difference is that all our medication is free for over 65s and some others. I've been on Co-codamol (apologies, iPad won't let me spell this correctly), Tramadol, and Gabapentin. My restlessness has been getting worse and worse for years, and a couple of weeks ago, I kicked a hole in my bed sheet during the night. So, a few days ago, I saw my GP, and he stopped the Tramadol (I'd been tolerating it well), and last night I took my first Mirapex. Oh, what a horrible experience! I felt dreadfully ill during the night, and when I got up this morning, I felt as if I had the flu. I was dizzy, sneezy, and in a cold sweat. Now I'm not sure whether to continue - maybe the side effects will settle."

• Anonymous
• January 1, 2011

"I've had restless leg syndrome for about 15 years and have tried several medications. Gabapentin worked most nights, but left me practically catatonic the next day. Klonopin did nothing to help my symptoms. Requip made me feel like I was going insane and really scared me. I gave Mirapex a high rating because it has completely eliminated all my symptoms. Unfortunately, I have severe nasal congestion as a side effect, which also keeps me up all night. If I don't take it, I can breathe, but my legs are jumping and jerking all night. If I do take it, my nose feels like it's filled with cement. Either way, I can't sleep. I guess it's back to the doctor to try something else."

• Anonymous
• September 1, 2011

"I have had restless leg syndrome all my life. I can remember when I was about 5 or 6 telling my mom my feet tickle... didn't know how else to explain it at that age. Today I am 39 years old and am only alive because of Mirapex. My RLS has become so severe that without this medication I would not sleep. One time I was without my medication and was up for 3 days straight. Ended up in the emergency room many times when I didn't have any medication just to get some form of relief. I currently take Mirapex 1 mg at night, but sometimes will have to take a half during the day. My RLS will bother me mid-afternoon at times and when it's really bad will go into my hands and forearms. I am eternally grateful for Mirapex despite the side effects of nausea, tired, and weak."

• Sar...
• Taken for less than 1 month
• May 2, 2013

"Delighted to hear others have benefited by taking Mirapex, I have had very mixed results. It certainly has alleviated my symptoms connected with Restless Legs Syndrome. But the relief came with a price. I became so nauseated that I was up all night, so after three nights I had to stop taking the medicine. I found Percocet the ideal replacement."

• Anonymous
• September 16, 2008

"Mirapex is a godsend. Before Mirapex, sleep was non-existent unless I took a sleeping pill. Now I get peaceful night's sleep. The only drawback is, it's expensive, and insurance barely covers any of the cost. But I can't live without it."