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Pneumococcal 20-valent conjugate vaccine and Fatigue: What Users Say

Brand names: Prevnar 20

Fatigue: mentioned by 7 users (23.3%)

Based on user experiences from 30 Pneumococcal 20-valent conjugate vaccine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 23.3%
chills 16.7%
headaches 16.7%
swelling 13.3%
fever 10.0%
nausea 10.0%
pain 10.0%
sore arm 10.0%
tiredness 10.0%

Reviews for Pneumococcal 20-valent conjugate vaccine

Showing 7 reviews tagged with "fatigue". Clear filters to view all 30 reviews.
Commonly mentioned side effects
  • D W...
  • Taken for less than 1 month
  • April 6, 2023

For Pneumococcal Disease Prophylaxis "I experienced soreness and redness in a 4-inch area around the injection site that lasted about 10 days. I also experienced some intermittent headaches on one side of my head, some swelling and puffiness under the eye on the same side, fatigue, and no energy. I did not realize this vaccine was so new and would not have received it if I had been informed of this by my provider who recommended it."

1 / 10
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45 Report
  • SBC...
  • Taken for less than 1 month
  • February 20, 2025

For Pneumococcal Disease Prophylaxis "Received the Prevnar 20 vaccine yesterday during my physical. Active, 56-year-old female with emphysema (thankfully no symptoms so far). Side effects were pain at the injection site, headache, and fatigue for a day. I am glad this vaccine is available, and it’s absolutely worth it to me, especially since it’s a one-time deal."

10 / 10
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1 Report
  • Tim...
  • Taken for 10 years or more
  • October 19, 2024

"I had my Prevnar 20 shot on 10-17-2024. I had a little bit of a sore arm, fatigue, and headache that all went away after about 36 hours. To me, it was worth the protection getting the shot. Everything in life entails a risk."

10 / 10
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2 Report
  • dko...
  • Taken for less than 1 month
  • February 27, 2023

For Pneumococcal Disease Prophylaxis "Terrible. I have had fatigue, malaise, headaches, muscle joint pain, and dizziness for days."

1 / 10
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24 Report
  • dko...
  • Taken for less than 1 month
  • February 27, 2023

For Pneumococcal Disease Prophylaxis "Terrible. I have had fatigue, malaise, headaches, muscle joint pain, and dizziness for days."

1 / 10
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24 Report

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  • clm...
  • Taken for 1 to 6 months
  • November 17, 2022

For Pneumococcal Disease Prophylaxis "This vaccination caused an exacerbation of my chronic fatigue syndrome (CFS), where other vaccinations in the past, such as for COVID-19, did not. Extreme fatigue, sore throat, possibly more."

5 / 10
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23 Report
  • Ele...
  • Taken for 10 years or more
  • March 29, 2024

For Pneumococcal Disease Prophylaxis "Had onset of fatigue 6 hours after injection. This is the third day that my energy is compromised. Site of injection subsided within a day."

5 / 10
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3 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.