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Pneumococcal 20-valent conjugate vaccine Pregnancy and Breastfeeding Warnings

Medically reviewed by Drugs.com. Last updated on Mar 4, 2022.

Pneumococcal 20-valent conjugate vaccine is also known as: Prevnar 20

Pneumococcal 20-valent conjugate vaccine Pregnancy Warnings

The manufacturer makes no recommendation regarding use during pregnancy.
According to some authorities, this drug should not be used during pregnancy unless the benefit outweighs the risk to the fetus.

US FDA pregnancy category: Not assigned

Risk summary: No data available on use of this drug in pregnant women to inform a drug related risk.

Comments:
-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects.
-An animal developmental toxicity study of administration of a single human dose prior to mating and during gestation revealed no evidence of harm to the fetus.

Animal studies of developmental toxicity had female animals given an intramuscular injection of 0.5 mL (the single human dose) of this vaccine twice prior to mating (17 day and 4 days prior to mating) and twice during gestation (gestation days 10 and 24); no adverse effects on pre-weaning development were observed and there were no vaccine-related fetal malformations or variations.

US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Pregnancy categories A, B, C, D, and X are being phased out.

See references

Pneumococcal 20-valent conjugate vaccine Breastfeeding Warnings

The manufacturer makes no recommendation regarding use during lactation.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments:
-There is no information regarding this drug on the presence in human milk, the effects on a breastfed infant, or effects on milk production.
-Consider the developmental and health benefits of breastfeeding along with the mother's clinical need for this medication as well as any potential adverse effects from this drug or the underlying maternal condition.

See references

References for pregnancy information

  1. "Product Information. Prevnar 20 (pneumococcal 20-valent conjugate vaccine)." Pfizer U.S. Pharmaceuticals Group (2021):

References for breastfeeding information

  1. "Product Information. Prevnar 20 (pneumococcal 20-valent conjugate vaccine)." Pfizer U.S. Pharmaceuticals Group (2021):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.