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Osphena and Night Sweats: What Users Say

Night sweats: mentioned by 6 users (13.3%)

Based on user experiences from 45 Osphena reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 31.1%
weight gain 28.9%
cramps 20.0%
headaches 17.8%
bloating 13.3%
night sweats 13.3%
sweating 11.1%
discharge 6.7%
dryness 6.7%
fatigue 6.7%

Reviews for Osphena

Commonly mentioned side effects
  • Mar...
  • Taken for 1 to 6 months
  • April 9, 2015

For Dyspareunia "This medication started working immediately. Within three days, more moisture. Within the next week, my interest in sex returned and I felt a major decrease in pain. I have been using this medication for 5 months now. Am I completely discomfort free? No. However, with the use of a lubricant like coconut oil (the best I've used) or olive oil (second best), both of which are the most like the body's natural moisture and some modifications in position or speed, this medicine has been a miracle for us. Unlike when we were young, it takes more preparation to be physically ready for intercourse, but we've adapted to those changes. I was/am frightened by the potential side effects. The only drawback for me at this point is an increase in night sweats."

10 / 10
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101 Report
  • Wwo...
  • Taken for 1 to 2 years
  • July 24, 2019

For Vaginal Dryness "I have taken this for over a year. Initially, other than being a little more tired than usual, I was pleased with the results. The last six months, I have had severe night sweats and still feel overall tiredness. I am physically more fit than many women my age (66). I decided to quit this and try non-hormone alternative treatments. After three days, I did not have the night sweats. Will see if my energy returns!"

5 / 10
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32 Report
  • KJa...
  • Taken for 6 months to 1 year
  • September 23, 2019

For Atrophic Vaginitis "This medicine did help with dryness, but after 6 months of night sweats and hot flashes (worse than I ever experienced during menopause), it just wasn’t worth it. Then came a horrible case of BV, which was the final straw."

4 / 10
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18 Report

Frequently asked questions

  • Sun...
  • Taken for 1 to 6 months
  • September 13, 2020

For Vaginal Dryness "I’ve been taking Osphena for 1 month now. The first week started the hot flashes and night sweats during the night that wake me. Muscle spasms in my legs. Weight gain and feeling bloated. My Dr advised to continue for at least 12 weeks, not sure if I can manage 2 more months of side effects."

4 / 10
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9 Report
  • Lab...
  • May 2, 2019

For Perimenopausal Symptoms "I started Osphena to maybe help with worsening prolapse... along with pelvic PT. Then, 1.5 years later, I have had a hysterectomy due to endometrial cancer, also, I have had night sweats and hot flashes."

2 / 10
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9 Report
  • Cal...
  • Taken for 2 to 5 years
  • January 20, 2023

For Vaginal Dryness "I have been taking this for 3+ years, hoping to experience less painful intercourse. I cannot detect any benefits of taking Osphena, and after reading reviews, I am wondering if my severe hot flashes, night sweats, leg cramps, fatigue, and weight gain are related. I'm stopping this drug today. It may not be causing all of the above symptoms, but it certainly isn't providing any detectable benefits. I'm done."

1 / 10
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1 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.