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Osphena and Fatigue: What Users Say

Fatigue: mentioned by 3 users (6.7%)

Based on user experiences from 45 Osphena reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hot flashes 31.1%
weight gain 28.9%
cramps 20.0%
headaches 17.8%
bloating 13.3%
night sweats 13.3%
sweating 11.1%
discharge 6.7%
dryness 6.7%
fatigue 6.7%

Reviews for Osphena

  • Jan...
  • Taken for 1 to 6 months
  • July 31, 2019

For Dyspareunia "At first, it was definitely helping with dryness. Then I was wetting my pants all the time, and I got a horrific yeast infection -- took three rounds of medication to fix it. I also felt stressed -- lack of energy and weakness. I didn't realize how bad that had gotten until I went off it. The yeast infection was the final straw. Then, after being off it for a week, ovarian pain began, and I now will need to get this checked off. I went through early menopause (46). I think I have exhausted all options for the pain at this point."

1 / 10
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31 Report
  • Cat...
  • Taken for 1 to 6 months
  • December 18, 2019

For Vaginal Dryness "I am having horrible headaches, leg cramps, drenched in sweat to the point where I am waking up in the middle of the night dehydrated, fatigue, and had none of that before taking. It started about a week into taking the pills. I am going to stop immediately and search for an alternative."

3 / 10
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20 Report
  • Cal...
  • Taken for 2 to 5 years
  • January 20, 2023

For Vaginal Dryness "I have been taking this for 3+ years, hoping to experience less painful intercourse. I cannot detect any benefits of taking Osphena, and after reading reviews, I am wondering if my severe hot flashes, night sweats, leg cramps, fatigue, and weight gain are related. I'm stopping this drug today. It may not be causing all of the above symptoms, but it certainly isn't providing any detectable benefits. I'm done."

1 / 10
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1 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.