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Ofatumumab and Tiredness: What Users Say

Brand names: Kesimpta, Arzerra

Tiredness: mentioned by 6 users (8.1%)

Based on user experiences from 74 Ofatumumab reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 13.5%
chills 9.5%
fatigue 9.5%
fever 9.5%
flu-like symptoms 9.5%
migraine 9.5%
tiredness 8.1%
nausea 6.8%
body aches 4.1%
itching 4.1%

Reviews for Ofatumumab

Commonly mentioned side effects
  • Mar...
  • Taken for 1 to 6 months
  • October 24, 2024

For Multiple Sclerosis "I have completed the first four injections. Based on everything I read, I was extremely worried about severe side effects. However, I was astonished at what a mild experience I have had. For me, the side effects have been more minimal than after a flu vaccine. I felt a bit more tired and had a headache. That was it. I injected on a Friday night, I felt a bit weak on Saturday. Sunday improved and Monday I was good to go to work. If I had known this, I would've started the medication many months earlier. It was negative reviews that put fear into me. This is just my experience, but so far I would recommend it. My doctor has scheduled an MRI for three months after I started the medication, and hopefully, it will show that it's working!"

10 / 10
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9 Report
  • LuL...
  • Taken for less than 1 month
  • May 20, 2022

For Multiple Sclerosis "I have taken my first dose two days ago. Due to COVID, insurance, and medication shortage, I was without any medication for 7 months. Begged for a steroid treatment, which I hate, and my neurologist wouldn’t do it. I have been nauseous, with a mild headache, very tired, and HOT! It’s humid here (SC), and the night sweats were so bad. The reviews have been helpful. I will know more when I get to my second and third dose. Not given up yet. Keep your fingers crossed!"

6 / 10
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27 Report
  • Dia...
  • Taken for less than 1 month
  • November 28, 2022

For Multiple Sclerosis "I have finished the 3-week shots. Each time, it did get better. I still get tired on the 5th or 6th day after the shot. I was taken off Ocrevus because getting an infusion all at once was shocking my body, and I have a weak stomach to begin with. In the beginning, I know there will be some side effects until your body gets used to it and trying to work with it. I am hoping this will keep my MS steady. Good luck, everyone. Think positive."

7 / 10
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20 Report

Frequently asked questions

  • Kat...
  • Taken for 1 to 6 months
  • June 15, 2024

For Multiple Sclerosis "I have had eight doses, including the loading doses. My side effects have mainly been exhaustion, though I have slowly lost my appetite, and recently felt highly nauseous. My MS symptoms are steadily declining, pain, weakness, stiffness, etc., but without Kesimpta I may be a whole lot worse. The medication needs at least a year to really work too. Overall, without any other real choices, I am happy to keep having the Kesimpta injections."

6 / 10
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8 Report
  • aba...
  • Taken for 1 to 6 months
  • February 22, 2025

For Multiple Sclerosis "I was very hesitant to try this with all the negative reviews. I know everyone is different, so some will get the side effects and some will not. I treated this the same way I treated Rebif when I was on it years ago. I took an IBP 800, took the shot, and went on with my day. I had no side effects since I took the IBP. If you've ever been on the shots, it's the same, just a smaller needle and I didn't even feel it. I was on Adagio before this for 7 years, and it did well until the end. It made me tired, so I took it at night, and it made my hair thin and nails brittle, but they all seem to do that. I would highly recommend either of these meds. Side effects are not as bad as people describe them as! With Kesimpta, just take Advil or Tylenol beforehand and you'll be fine."

10 / 10
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4 Report
  • Chr...
  • Taken for less than 1 month
  • May 12, 2022

For Multiple Sclerosis "Took my first dose, just felt a little tired. Feels like it’s doing something to my legs, have woken up with cramps, not spasms. Hoping this is a positive sign!"

4 / 10
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19 Report

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