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Ofatumumab and Nausea: What Users Say

Brand names: Kesimpta, Arzerra

Nausea: mentioned by 5 users (6.8%)

Based on user experiences from 74 Ofatumumab reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 13.5%
chills 9.5%
fatigue 9.5%
fever 9.5%
flu-like symptoms 9.5%
migraine 9.5%
tiredness 8.1%
nausea 6.8%
body aches 4.1%
itching 4.1%

Reviews for Ofatumumab

Commonly mentioned side effects
  • Anonymous
  • Taken for 1 to 6 months
  • January 11, 2023

For Multiple Sclerosis "I completed Kesimpta’s three loading doses in November of 2022. For each injection, I took one Tylenol, one Benadryl, and a Pepcid later on - I think this definitely helped with the fever, body aches, and nausea. I was previously on Ocrevus but was unable to walk out of the facility after my last infusion (I had switched from the 6/7 hour infusion to the 4 hour one). I didn’t take any disease-modifying drugs for the next year until Kesimpta in November 2022 at the suggestion of a neuro. My lymph nodes in my neck/jaw have been swollen since November 8 (date of first injection), and I have had different infections since (a double ear infection, recurring upper respiratory infections). I feel like I always have a mild fever and am kind of miserable now, haha. I’ve also lost my voice several times, which is the first time that’s happened in my life! My lymph nodes are swollen to the point that it is also making it painful to speak. 0/10"

1 / 10
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37 Report
  • Jac...
  • Taken for less than 1 month
  • December 2, 2022

For Multiple Sclerosis "The 1st dose was rough for the loading dose. 1st one, I experienced chills and shakes that were uncontrollable. The absolute worst headache I have ever experienced, and I felt like I needed to vomit but couldn't. Taken at 1900, awoke at 2300, and I wasn't able to fall asleep again until 0400. Did not want to take the next dose, but did. Minor headache, no chills, taken at 1900, headache woke me at 0300, but I was able to get up and take acetaminophen and back to bed. 3rd dose, I had read about taking Benadryl 1 hour prior to dosing with acetaminophen. Taken meds at 1800, dosed at 1900. Woke about 0330, but was able to drink some water and went back to bed. By the 3rd dosing, I believe I was acclimated to the drug, but I am worried about a repeat of the 1st experience now that it is going to go to monthly. I do not see improvements in symptoms, e.g., fatigue, room spinning, tingling in arms and legs. I will update after about 6 months of injection."

8 / 10
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31 Report
  • LuL...
  • Taken for less than 1 month
  • May 20, 2022

For Multiple Sclerosis "I have taken my first dose two days ago. Due to COVID, insurance, and medication shortage, I was without any medication for 7 months. Begged for a steroid treatment, which I hate, and my neurologist wouldn’t do it. I have been nauseous, with a mild headache, very tired, and HOT! It’s humid here (SC), and the night sweats were so bad. The reviews have been helpful. I will know more when I get to my second and third dose. Not given up yet. Keep your fingers crossed!"

6 / 10
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27 Report

Frequently asked questions

  • Kat...
  • Taken for 1 to 6 months
  • June 15, 2024

For Multiple Sclerosis "I have had eight doses, including the loading doses. My side effects have mainly been exhaustion, though I have slowly lost my appetite, and recently felt highly nauseous. My MS symptoms are steadily declining, pain, weakness, stiffness, etc., but without Kesimpta I may be a whole lot worse. The medication needs at least a year to really work too. Overall, without any other real choices, I am happy to keep having the Kesimpta injections."

6 / 10
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8 Report
  • Bir...
  • July 23, 2021

For Multiple Sclerosis "On my 1st dose, chills, nausea, vomiting. Will not be taking again."

1 / 10
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31 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.