Skip to main content

Naproxen and Heartburn: What Users Say

Brand names: Aleve, Naprosyn, Naproxen Sodium DS, Anaprox-DS, Naprelan, Aleve Back and Muscle Pain, Flanax Pain Reliever, EC-Naprosyn, All Day Relief, Comfort Pac with Naproxen, Pamprin All Day Relief, Aflaxen Midol Extended Relief All Day Pain Relief …show all brand names

Heartburn: mentioned by 10 users (1.5%)

Based on user experiences from 683 Naproxen reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 5.7%
upset stomach 5.7%
pain 3.5%
dizziness 3.1%
vomiting 2.3%
headaches 2.0%
stomach pain 1.9%
bleeding 1.5%
heartburn 1.5%
swelling 1.5%

Reviews for Naproxen

Commonly mentioned side effects
  • She...
  • October 16, 2017

For Tendonitis "I went to the doctor after having pain in my elbow. I thought it was tennis elbow, but my doctor dismissed it as tendonitis and quickly prescribed me Naproxen 500 mg to be taken twice daily. I made sure I took it after food, and on the third day in, I started experiencing stomach pain and indigestion/heartburn. This continued over the next 2 days with increased pain and feeling bloated. On the fifth day, stiffness started creeping in all over my body, so bad that I couldn't take my own clothes off. It is now day 6. I haven't taken any tablets and had to spend the day in bed. It has even made my breasts feel very sore. I feel as though I've been in a horrendous car crash. I will definitely not be taking this drug ever again. I'm usually a very fit 49-year-old."

1 / 10
Was this helpful?YesNo
11 Report
  • Sha...
  • Taken for less than 1 month
  • May 6, 2016

For Tendonitis "I had a severe side effect of naproxen. I had some inflammation in my left knee, and it was bothering me when sitting down, so I showed it to the doctor. I was prescribed naproxen 500 mg twice a day for 5 days. I took three tablets in 36 hours (making sure after lunch and dinner and with plenty of water), and after taking the second pill on the first day, I had a terrible time. I couldn't sleep, had a severe funny feeling in my stomach, right under my ribs and just above the stomach. I had a strong empty-stomach feeling all the time. The feel for my whole body was terrible, and I felt super sick. I didn't throw up or have loose motions, but I had lots of stomach pain and extreme heartburn. I stopped taking the medicine after 3 pills and informed my doctor."

1 / 10
Was this helpful?YesNo
15 Report
  • Smb...
  • Taken for less than 1 month
  • October 16, 2015

For Back Pain "I am pretty sure this medication is just acid in pill form. And not the fun kind either. No. I took this medication for severe arthritis and fibromyalgia, and 15 minutes later my whole esophagus feels like it's on fire. I took the medication with food as prescribed, and still, this is the worst heartburn I have ever had in my life. I used to have severe ulcers, and I know when a medication is burning my stomach lining. No sir. No more ulcers for me, thank you. I also had the alarming sensation of hearing everything while underwater. I spent the whole week asking people to repeat themselves because their voices sounded muffled. That with severe ringing in the ears and persistent nausea - I quit this medication after a week."

4 / 10
Was this helpful?YesNo
13 Report

Frequently asked questions

  • Anonymous
  • June 23, 2009

For Pain "So far, so good for chronic neck pain/spasm. It's the first time I've tried it, and my neck has never felt better. The only side effect has been mild heartburn, but I'd rather that than not being able to move my neck."

9 / 10
Was this helpful?YesNo
14 Report
  • elj...
  • Taken for 5 to 10 years
  • December 14, 2020

For Osteoarthritis "I’ve been taking these naproxen on and off for years relating to joint pain. Most prominent in my back, feet, and knees. I’ve finally said enough is enough. I might as well be popping candy. They are a complete waste of time. I get zero benefit from them but am fortunate that I don’t get any side effects, with the exception of heartburn. I know several people that take them, and no one can say in my circle they are a benefit to them. I’ve now had to resort to Nurofen Plus, which financially is crippling, but they at least give me some very mild relief."

1 / 10
Was this helpful?YesNo
4 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Kev...
  • September 9, 2015

For Tendonitis "Was prescribed drug for Achilles tendinitis, 500 mg Naproxen twice a day with omeprazole 20 mg. Should never have taken this as it caused heartburn and stomach infection, stopped taking on the second day and still have not recovered from stomach problems over 2 months later despite taking other remedies. Disgusting drug!!!"

1 / 10
Was this helpful?YesNo
12 Report
  • nap...
  • Taken for less than 1 month
  • January 1, 2023

For Osteoarthritis "Omg. What a horrible drug. I was prescribed this along with lamproserol to ease my osteoarthritis pain in my upper back. I only took them for three days. It gave me the worst heartburn ever and terrible acid reflux. I will never take them again."

1 / 10
Was this helpful?YesNo
1 Report

More FAQ

  • Rho...
  • Taken for less than 1 month
  • July 10, 2018

Naproxen for Back Pain "Relieved back pain but resulted in bad heartburn."

6 / 10
Was this helpful?YesNo
10 Report
  • Mar...
  • Taken for less than 1 month
  • January 15, 2017

For Pain "Terrible heartburn and nausea after three doses (pills). Stopped on the advice of doctor."

3 / 10
Was this helpful?YesNo
4 Report
  • kas...
  • January 4, 2016

Naproxen for Juvenile Rheumatoid Arthritis "Didn't help at all, it did give me terrible heartburn, though."

1 / 10
Was this helpful?YesNo
1 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.