Naltrexone for Fibromyalgia User Reviews (Page 3)
Brand names: Vivitrol
Naltrexone has an average rating of 6.9 out of 10 from a total of 65 reviews for the off-label treatment of Fibromyalgia. 62% of reviewers reported a positive experience, while 26% reported a negative experience.
Reviews for Naltrexone
- katie
- Taken for 1 to 6 months
- September 10, 2021
"I have tried the lowest possible doses of Naltrexone. I have tried taking this drug many different ways. It gave me horrible diarrhea & cramping ( lost 5 lbs in almost 2 weeks), and severe paranoid anxiety. Like I have never experienced before. It did all of this yet never touched my pain. It was still there. This drug was worthless."
- Kate
- Taken for 1 to 2 years
- February 12, 2022
"Unusual tiredness that did not come on until the past 6 months that I could barely get out of bed. Motivation: gone. This will slowly sap you dry til your so weary you do t know what from bc it used to work. Slick drug, be careful as it brings on chronic fatigue."
Frequently asked questions
- What is low dose naltrexone (LDN)?
- What happens if you drink alcohol while taking naltrexone?
- What to avoid when taking naltrexone?
- Should I take naltrexone in the morning or at night?
- SC...
- Taken for less than 1 month
- August 12, 2021
"I experienced some odd side effects: drowsy all day on low dose, hard time working as all I wanted to do was sleep. No pain relief for fibromyalgia, instead I woke up each morning with stiffness and pain in lower limbs to knees and neck and upper arms pain to elbow. In addition I felt down most of the time, just depressed and blue. I also had diarrhea throughout the day. Bizarre side effects included the limb stiffness and unusually frequent sexual thoughts, not normal for me. My appetite was lower and I slept longer at night. It was very difficult to work though with drowsiness all day, made pushing through heavy fatigue difficult. I drove my car to do errands nearby and had trouble navigating and drove over curbs a couple of times. That scared me. So finally with these side effects in a two week period I stopped taking the med. My side effects are unusual from what I have read."
- Jamie...
- Taken for 1 to 6 months
- May 31, 2022
"I have slowly eased up to 4.5 mg of naltrexone to treat fibromyalgia associated with Chronic Inflammatory Response Syndrome (CIRS) disease from chronic mold exposure. As my dosage increased I developed more diarrhea and neck and back pain. During this time I also stopped gluten and was diarrhea free during the first week of stopping the gluten but I would have terrible diarrhea beginning again several days later. CIRS is a chronic inflammatory disease so this may be contributing to the problem but the naltrexone side effects of rapid heartbeat, diarrhea, severe anxiety, fatigue, depression, and agitation are all very real and scary for me. Because this is not an addictive drug I will stop immediately. I’m surprised my doctor didn’t suggest going off of this drug (vs all my other drugs) when I began to feel this sick with the very common and noted side effects of naltrexone."
Are you taking this medicine?
- Shari...
- Taken for 1 to 6 months
- December 27, 2021
"I start this medication as 12 years with chronic fatigue and managed it until recently where I had to leave my job. I started on 0.5mg and worked up by 0.5 every 10 days. I saw an immediate improvement however I’m now on 3mg and I feel like the energy is decreasing again. Has anyone had this? Does it mean I need to decrease the dose or increase higher than 3mg? Thanks!"
- Winnie
- May 16, 2022
"I have been prescribed Naltrexone 4mg (have worked my way up to 4mg slowly twice now) for fibromyalgia. I have epilepsy (controlled w/ tegretol for over 35 years), POTS, hearing loss and tinnitus. My experience with Naltrexone hasn't been positive. The first round I experienced leg cramps and crackling pain (nerve pain I think) and second time round it's been more of the same although now that I am at the 4mg dose again I am having pain (mostly nerve type pain) episodes all over my body (mostly legs, hips, arms, across the shoulders). This makes sleeping difficult although I don't believe I am suffering from insomnia, yet. I also do not notice any increase in energy and I believe I have more stiffness in the morning time. Anyhow I am going to stop taking it. I was wondering if anyone else has epilepsy and if such a low dose could react with anti-seizure meds!? Thank you for reading and or responding. It's been enlightening reading people's experience with this medication."
More FAQ
- Does naltrexone cause weight gain?
- Acamprosate vs naltrexone: How do they compare?
- How does naltrexone make you feel?
- How long does naltrexone take to work?
- ljcro
- Taken for 1 to 2 years
- August 16, 2016
"highly successful, got me off 90% of pain meds, couldn't live without it."
- goodf...
- Taken for 2 to 5 years
- February 22, 2018
"put my autoimmune condition into remission When from c-react over 200 to 17...life is finally good"
- Lori
- Taken for 5 to 10 years
- May 15, 2018
"This has absolutely been a life changer! I could not live without it."
- laura...
- Taken for 1 to 6 months
- February 10, 2016
"I have been on naltrexone for 5 months, and it's not done a good job of helping with my pain."
- Crcl
- Taken for less than 1 month
- June 8, 2019
"I’ve stop tramadol after 10yrs for my fibromyalgia to start naltrexone this past Monday 6/3/19 and OMG "
- greek...
- Taken for less than 1 month
- September 25, 2015
"Chills, Diarrhea, vomiting."
- Anonymous
- November 28, 2009
"This did nothing to help my fibromyalgia."
- honey...
- Taken for 6 months to 1 year
- November 7, 2022
"I use naltrexone for ME. Life changing No fatigue No difficulty with information processing No brain fog Increased energy"
- Kim
- April 30, 2021
"I am so happy my doctor prescribed this. I just needed to find the dosage that worked for me and ever since things improved tenfold."
- Mf3
- Taken for 6 months to 1 year
- August 17, 2021
"Greatly reduced nerve pain. 4.5G notice positive effects after about 4 months."
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
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"I’ve been taking LDN for my autoimmune condition, Graves’ disease, for over 5 years now at 4.5 mg, just recently down to 3 mg. I’ve never gone completely into remission this time around though I’ve gotten close, but my numbers have been all over the place. I feel like it may have improved my sleep a bit, but since it’s hard to see whether or not it’s actually helping my autoimmune disease, I’ve tried to stop taking it various times over the last few years and wake up at night, a few hours in, with body aches, restlessness, and stiffness every time I don’t take it or forget to take it. I’ve searched and can’t find anyone else who has experienced this. It doesn’t seem like a good thing that I’m experiencing these withdraw symptoms when I don’t take LDN. If I take it when I wake up in the middle of the night, the symptoms stop.... I don’t experience any negative effects while taking LDN. Are these LDN withdraw symptoms?"