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Metformin / saxagliptin User Reviews & Ratings

Brand names: Kombiglyze XR

Metformin / saxagliptin has an average rating of 5.0 out of 10 from a total of 17 reviews on Drugs.com. 29% of reviewers reported a positive experience, while 41% reported a negative experience.

Condition Avg. Rating Reviews Compare
Type 2 Diabetes
4.7
 16 reviews for Type 2 Diabetes 158 medications

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Reviews for Metformin / saxagliptin

  • Mau...
  • Taken for 1 to 6 months
  • June 16, 2013

For Type 2 Diabetes "Recently diagnosed with type 2 diabetes. Doc put me on 2.5 mg, with little results but side effects. Raised it to 5 mg and I feel worse. I am using sample packs and insurance will not cover. I have noticed improvement in my sugar levels, but I have felt worse now having started the pills. Nausea, soft stool, headache, dizzy. All of these and sugar reads only 152. Also, I don't feel rested when I'm sleeping."

5 / 10
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16 Report
  • sou...
  • July 16, 2015

For Type 2 Diabetes "I've been on Kombiglyze XR for 3 years and have never felt better. All other drugs caused stomach pain and diarrhea. For the first two years, my doctor added glimepiride, then Lantus 40 units. After changing my diet, I'm off glimepiride and only using 12 to 14 units of Lantus, working on getting off completely. Oh, and I've lost 30 pounds. No more night sweats or high and low blood sugars. Did I mention my blood sugars have dropped from 7 to 6 on my A1C? Two in a row! Hope by next year I will be on 2.5/500 Kombiglyze XR once daily. After 8 years, finally something that has worked for me!"

7 / 10
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9 Report
  • Ndu...
  • May 22, 2014

For Type 2 Diabetes "My doc just wanted my A1C to go down from 6.0. After years of Glucophage, he changed me to this great pill. It has been 2 weeks, and I have not felt so strong and healthy. Besides little stomach discomfort an hour after I take it, my morning blood sugar reading has gone from 130 to 105 and below. In another 2 weeks, I will know my new A1C reading. I think I am going to love this medicine."

9 / 10
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8 Report

Frequently asked questions

  • PIZ...
  • Taken for 2 to 5 years
  • April 25, 2015

For Type 2 Diabetes "Sugar - 117, and sometimes it will spike to 254 for a half day, can't sleep, no energy, joint pain, intense ankle pain. Have to wear custom-made leather braces. Limits my walking to 5-10 minutes, tired of the foot pain, joint pain climbing up stairs in our car."

6 / 10
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6 Report
  • Sud...
  • December 10, 2015

For Type 2 Diabetes "This has been a great drug for me since I started a month ago. I have been diabetic for the past 1.5 years. I first used insulin for a month and then Triglynase 2 mg, Zoryl M2. I usually hit low sugars when I took Zoryl M2. But now, with Kombiglyze 5/1000, I am feeling much better."

10 / 10
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2 Report

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  • MeM...
  • Taken for 1 to 6 months
  • July 6, 2017

For Type 2 Diabetes "I was taken off Invokamet and started Kombiglyze/metformin, and my normal waking sugar has usually been a little high (140-180), but after being on this, it's in the 200's and 300's waking and stays high most of the day (even with small doses of Humalog). It's been crazy, and I'm looking at changing to something different now :/"

3 / 10
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1 Report
  • raf...
  • April 24, 2016

For Type 2 Diabetes "Dr. prescribed this medicine with lots of confidence, and my A1C was 8.8. Sugar levels dropped, but I had a horrible time taking it. Within the 3 weeks that I took it, I had woken up at least 5 times in the middle of the night with severe acidity and nausea, with constipation. Felt like I would die. Had to ask the doctor to stop it."

4 / 10
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1 Report
  • Anonymous
  • January 27, 2012

For Type 2 Diabetes "I have never felt as well on any other medicine or been able to keep my sugar level as consistent as it is now throughout the day."

10 / 10
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47 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • July 9, 2012

For Type 2 Diabetes "Dr. put me on this, and within 3 months, my A1c went from 6 to 8.6. Continued for 6 more months, and blood sugars are high."

1 / 10
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35 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • September 19, 2013

For Type 2 Diabetes "I have minimal side effects, and my sugar levels went down."

10 / 10
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14 Report
  • laf...
  • June 20, 2014

For Type 2 Diabetes "I have been taking since May, and I am sick every day. I have never felt this bad taking any medication, my doctor is going to have to put me on something different."

1 / 10
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6 Report
  • edz...
  • Taken for 1 to 6 months
  • June 6, 2018

For Type 2 Diabetes "I was okay with metformin and taking it since 1997, and my new doctor switched me to Kombiglyze XR. Now I'm having foot pain, upper respiratory infection, and left eye redness and pain."

1 / 10
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2 Report
  • Dr...
  • October 4, 2012

"This medicine is great, our patients no longer have to worry about if they miss a dose because it's taken once a day."

10 / 10
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6 Report
  • Tub...
  • Taken for 1 to 6 months
  • December 7, 2015

For Type 2 Diabetes "Chest pain increased. Vision changed for the worse. Halo around lights at night. Creatinine, serum went up. BUN/creatinine ratio went up."

1 / 10
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2 Report
  • Mis...
  • Taken for less than 1 month
  • November 1, 2016

For Type 2 Diabetes "I have dizziness and lightheadedness most of the time. On the other hand, my blood sugar is significantly lowered by about 90%. I still have work to do."

5 / 10
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  • WRC...
  • Taken for 1 to 6 months
  • March 7, 2018

For Type 2 Diabetes "Ineffective, blood sugar readings have actually gone up, lethargic, chest and shoulder pain, memory loss. Don't recommend."

1 / 10
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  • Jan...
  • Taken for 1 to 6 months
  • April 16, 2018

For Type 2 Diabetes "I was taken off this medication due to getting chronic pancreatitis. Please look up the symptoms for chronic pancreatitis, type 2 medication can cause this awful disease."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.