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User Reviews for Lysine to treat Herpes Simplex

Also known as: L-Lysine, L-Formula

Lysine has an average rating of 8.2 out of 10 from a total of 18 ratings for the treatment of Herpes Simplex. 72% of users who reviewed this medication reported a positive effect, while 11% reported a negative effect.

Lysine Rating Summary

8.2/10 average rating

18 ratings from 20 user reviews.

Compare all 45 medications used in the treatment of Herpes Simplex.

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Reviews for Lysine

Anonymous November 11, 2011

“I've had herpes for 15 years and used to suffer with painful outbreaks. When searching the web, I found out about Lysine. I don't take it daily because I rarely have outbreaks, but I probably will. Currently, I've been taking 4 500 mg tablets daily when I feel that an outbreak is coming on. Either the outbreak doesn't come at all or it is less severe and goes away after a day or two. I also take Vitamin C with the Lysine and it's been very successful. I think I may take a Lysine vitamin daily to avoid the outbreaks altogether.”

10 / 10
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PLEASE READ January 19, 2020

“DO NOT USE. This stuff completely depletes your bodies own immunity to the virus, your body can't fight it alone once you've taken the recommended dose for even a couple of weeks. To make it worse you have to keep upping the dose as the virus outsmarts it. If you stop even for one day or forget a tablet the lysine can't gain control becoming a never ending battle that you will wish you never started. I now have extremely painful outbreaks every couple of days. The skin is red raw, bleeding and broken. It has ruined my job, my relationship and my whole quality of life. Extremely high doses of antivirals do not even take the edge off because my body now has zero immunity. I also now severe shooting pains down there and pain in the backs of my legs making it difficult to walk. I would not wish this nightmare on my worst enemy. Please I urge you do not start taking these tablets just let your body build up its own defences because it will.”

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Paul124 December 20, 2014

“I've herpes for about 3 years now. Have been having more obs the last few years, up to 2 OBs per month. Tried lots, eating really well, exercising regularly, stress relief etc. Nothing was helping much. Now I take 500mg of lysine first thing in the morning and 500mg before bed. Not had an OB for 60 days! That is amazing for me. No groin pain either. This stuff rocks! Get on it! I also drink turmeric tea regularly which I think helps with the groin pain (by reducing inflammation and being good for your immune system). 95% of credit goes to lysine though!”

10 / 10
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WynterSun · Taken for 2 to 5 years January 10, 2017

“I've had cold sores since I was a child. It's embarrassing and ghastly to look at. I'm now 32 and I've figured out the best remedies to prevent or speed up healing time. The #1 best medication is L-lysine. I take 1000 mg capsules (Nature's Bounty) at the first sign of an itch, tingle or irritation. I take no chances! Since taking L-lysine I haven't had one form yet. Dry lips on windy days, runny nose and stress are my triggers. #2 is Ice. Freezing it prevents the blisters from forming. The virus thrives in warm, moist areas. Use #3 Rubbing Alcohol w/ ice to dry out sore. For those naturopaths, #4 Turmeric is great in stopping blisters from spreading. It's a natural anti-inflammatory and the virus is unable to thrive. Best of luck!!!”

10 / 10
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Happyvjaygurl25 July 18, 2016

“One day I got a severe headache..it lasted for 3 full days. I was tired could barely move pain all over.I developed a rash almost like chaffing on my inner thighs next to my lady parts. I knew it was herpes so I went and got tested and sure enough it was positive for simplex 2. Being 25 and only having two partners really narrowed down where I got I from. I am still with the person who gave it to me. Any who. I was prescribed generic valtrex acyclovir it cleared up the rash in about a week.. But it had harsh side effects.leg pain.stomach pain etc. I researched lysine and began taking it after my 10 days of acyclovir.it has been 3 months and no further outbreak.I had my cycle and felt that viral tingle..i increased the lying and no outbreak”

9 / 10
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MayAnne · Taken for less than 1 month January 11, 2017

“I've gotten cold sores since I was young. It's a common thing among a lot of people, but it happens to me normally once a year around winter. My lips end up drying out and when they get chapped that's when a cold sore ends up forming. I am not completely sure why, but whatever makes it lay dormant gets aggravated. I actually went to a local drug store to get a cold sore treatment when I found Lysine. Unfortunately, I didn't catch it in time but it took the pain and itching away almost immediately. It's shortened the amount of time it would normally take a cold sore to heal when the blisters have already formed. It's better than the other products I have used, and a lot more efficient.”

9 / 10
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Mrs Suds July 12, 2015

“After suffering with cold sores from my teens I took a three bottle course of one tablet a day, and I never got cold sores again until the last six months. I am now in my seventies and have had a couple mainly in my nostril,I put it down to stress now but will try another course.”

10 / 10
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Susieq60 April 12, 2016

“I hsve HSV1 on geitals from oral sex. I was in denial. 1 had 3 red spots in labia major..turn to ulcer state.. terrible burn during urination &.crazy tingly itchy. and red swollen vulva duffeted a week...I read about lysine. took 3 1000 mg per day.after 3 days marked reduction almost gone”

10 / 10
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Pocahontas · Taken for 10 years or more December 20, 2018

“At the 1st sign of a cold sore ( itchy bump ) I take 2000mg a day until it’s gone, 2 days max) then 1 a day for a week. I’ve had cold sores for as long as I can remember, since my toddler yrs, and as an adult, 3-4 times a yr I would get a cold sore that went up into my nasal cavity and cover my upper lip, creating a sore that would crack and bleed. Over time, they would eventually go away but it was an awfully painful experience to endure. I had a scar that was very visible, since it covered my top lip and I was very self conscious about it. 25 yrs ago, after trying all the prescriptions that the dr prescribed, a Walmart pharmacist saw recommend l-lysine. I have used it ever since and not only did it stop the sores it also removed the scar!!! I will forever be a devoted fan of l-lysine!!!!”

10 / 10
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Blessed beyond measure · Taken for 1 to 2 years May 17, 2016

“I get Cole sores when my immune level decreases. Some of them are large enough to give a zip code to. I have had them take up 1/2 my lip and creep to my chin. If I take 2400 mg (two 1200 pills) at the start, and 1 every day it either stops it or shortens it. I've tried many other otc meds but L-Lysine seems to work the best. Much more affordable than Abriva.”

10 / 10
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H8DryEye December 14, 2016

“Got herpes keratitis (cold sore in eye) twice. The Opthamologist I was seeing would just prescribe me the same medications for the genital herpes. Even though the meds helped clear it from my eye, it wouldn't completely get rid of it. I'll still feel a bit of pain in my eye. So I started using lysine. The 1st wk using it, my pain went away. But wasn't sure if it was the lysine since was using other otc vitamins also (for my dry eye). But stopped using it last wk and started feeling the pain again in my eye. Last night took 2/500mg of Lysine before sleeping and woke up with lesser pain. Was very surprised. Still experimenting with the dosage, so will be taking 2/500mg, 3x's a day for maybe 3 days and slowly drop the dosage to only 2x's a day”

5 / 10
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Joy42733 March 18, 2017

“I had been taking lysine for about 2 weeks for a viral infection when I noticed that my planters wart on my foot had completely healed, little moles in my face were gone, and yes my viral cold infection was gone. I can not say 100% that it was the lysine but I use it for all viral infections and have had great results.”

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Loulou · Taken for 1 to 2 years October 31, 2019

“I have taken lysine many times and while I started taking it daily to prevent cold sores, I started to feel like I had restless leg syndrome and my feet started to hurt. This went on for weeks until I realized it started are I began taking the lysine. As soon as I stopped taking it my legs and feet no longer ached. I figured I was getting too much in my body so that must have been the reason. I haven’t taken it in a long time and last night I took it again because I felt a blister coming. It prevented the fever blister, but the leg and foot pain returned. My experience is that it works great to prevent and reduce duration of fever blisters, but it causes lack of sleep because I keep having to stretch my legs during the night for relief and my feet hurt.”

6 / 10
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Alienmundo · Taken for 10 years or more July 3, 2017

“I tend to get blisters on or very close to my lips which is embarrassing and impossible to hide. Lysine hasn't helped to quell my Herpes Simplex-1, albeit it is surprisingly effective at decreasing the size and aggressiveness of the blisters. I've tried utilizing a daily dosage of ~1000mg everyday annually for three years paired with o-t-c medications(abreva,lysine creams) applied asap after noticing the dreaded tingle. I still managed to get seven to ten outbreaks annually which was the same as before starting daily use. Therefore I only take heavy doses(2-3000mg daily) when I may be lacking sleep, sick, stressed or going to be in the sun for a while. Usually about a week before a possible out break and continue until it's healed.”

3 / 10
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Mr News · Taken for less than 1 month June 27, 2020

“Began taking 500-1000mg twice daily to suppress a recurrent sore/bump on rear side of my palate. This increased greatly in recurrence due to immunosuppressive drugs for another condition. The lysine seemed to work for about a week, but now is possibly causing frequent stomach/gut pain and cramps. Might stop lysine and see if stomach cramps resolve, then resume dosing at lower level, maybe 250mg 2X daily. I skipped a dose or two to see what would happen, and the mouth sore came right back. But I'm not sure the stomach cramps are tolerable, since I already have Crohn's with a lengthy stricture...”

5 / 10
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Coop April 5, 2020

“This stuff really does work!! I just bought this today and put it on two hours ago and wow! Amazing. I had a really bad outbreak with blisters all around my lips and chin and it’s working already! I’ve never had a cold sore or an outbreak ever before and I was so worried and desperate to get rid of it and I tried everything and with this stuff I am happy and looking healthy.”

10 / 10
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nnn3 · Taken for 1 to 6 months February 26, 2020

“Lysine does work in suppressing the Herpes virus but if you REALLY want to get rid of the outbreaks, take Lecithin 2400 mg each day for a month. It works!!!”

10 / 10
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Long time user January 8, 2016

“I have used lysine over 36 years. It has always helped for my cold sores”

10 / 10
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JacqueD November 22, 2016

“I found lysine to be my miracle for relief of my genital herpes outbreaks.”

10 / 10
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Mickieeeee January 14, 2017

“This stuff is so awful do not waste your time I feel like it made my cold sores bigger and more painful. I am so mad that through all this pain and suffering waiting for this medicine to work”

1 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.

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