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Lupron and Hot Flashes: What Users Say (Page 2)

Reviews for Lupron

Commonly mentioned side effects
  • Try...
  • Taken for 1 to 2 years
  • February 23, 2016

For Endometriosis "I took it 8 years ago for fibroids, cysts, and severe endometriosis. I was on Lupron for a year after trying other options. I had hot flashes and joint pain, plus a lot of the other symptoms mentioned. Calcium and vitamin D helped with joint pain. The symptoms remained consistent while I was on the Lupron, however, even with the side effects, the year that I was on Lupron was the best I have ever felt. Finally, no more debilitating pain. I got pregnant after the 6-month weaning off period and had two kids. If endo is an inconvenience for you, maybe not the best drug. If endo is ruining your life, some side effects and symptoms are worth getting your life back. I am on it again and grateful that there is something out there that gives me relief."

9 / 10
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  • Mau...
  • Taken for 1 to 6 months
  • August 19, 2015

For Endometriosis "I've received my first round in June 2015. Almost immediately, I started experiencing side effects. Headaches, weight gain, hot flashes, constant sweating, mood swings, made my depression worse, now swollen legs and ankles, also severe joint pain. This is becoming unbearable, and I'm rethinking doing the next cycle. It's helped with my endometriosis, which I'm happy about, but these side effects are a...."

7 / 10
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14 Report
  • cj2...
  • November 22, 2015

For Endometriosis "This drug should be taken off the market. It kills your immune system, and the side effects never wear off. I had three injections in 2002 and am still suffering from what has happened to my body. The joint pain and hot flashes are unbearable. This medication has robbed me of enjoyment of life. Its only purpose is money for Big Pharma and ease of surgery for the doctor. No benefit to the patient at all. Do not take this, it will ruin your life."

1 / 10
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Frequently asked questions

  • mem...
  • Taken for 1 to 6 months
  • September 13, 2016

For Endometriosis "Was prescribed Lupron after endo surgery since not all growths could be removed. I was very scared to be taking it after I read about it (I cried in the doctor's office when getting the injection). But I ended up loving it. It stopped my periods and the pain, so my anemia was under control and I had so much energy! As for side effects, there was insomnia (but I was not tired from it, so it was OK) and hot flashes started after about two months - but that was nothing compared to the relief. I only got one 3-month shot, but the positive effects lasted for quite a bit. I hope to get another 3-6 months soon. I know there are risks to this, and everyone reacts differently, so I could not advise anyone to take it or not, but for me it was wonderful."

9 / 10
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12 Report
  • Lan...
  • December 28, 2016

For Uterine Fibroids "I am on a 3-month shot plan but monthly shots. I didn't want the 3-month all at once because I wanted to see how my body would react to it first. Shot given 12/07/16, and today is 12/28/16. The first week, I didn't really have any side effects, and I was really hopeful that this would be the worst. Wishful thinking didn't last long. Hot flashes, night sweats, chills, emotional wreck, and I believe slight headaches that come and go. BUT, on the contrary, less than a month and my fibroid has already physically shrank. I haven't seen the doc yet, but I can physically see that it shrank. My clothes are loose in the belt line area. My fibroid was the size of a small grapefruit (17 cm), but I really see a huge difference in shrinkage. Could be worse :/"

5 / 10
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  • Az-...
  • Taken for 1 to 6 months
  • May 29, 2020

"My prostate cancer was treated with radiation in 2003 but came back around 2013, and PSA has climbed all the way to 14.8 now in 2020, so thought it was time to try something. Lupron gave me horrible side effects, including severe hot flashes, about 2 every hour, 24/7, nausea, dizziness, tiredness, weight gain, constant urination, very low libido, etc. On the positive side, I only had one 3-month shot, and my PSA went from 14.8 down to 0.3, however, I am not going to take another shot and will see how it goes. Will try to eat and exercise better."

3 / 10
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  • Mis...
  • July 12, 2015

For Endometriosis "I've been on Lupron twice in 6 years. The first time was 2008, and I didn't experience any symptoms. I was extremely happy about that. Like most of you reading, all the side effects had me a little on edge. The second time my doctor suggested that I get on it (Dec 2014), I agreed with no problem. Hoping that will be the same experience as the first time. Ohhhhhh, but it wasn't. I had hot flashes, night sweats, and weight gain. I couldn't wait until those 6 months were over. Unlike the first time, 3 months off Lupron, my cycle started, and 2 weeks later, two cysts, 7.5 cm. I was devastated and in so much pain, and before you knew it, I was having surgery. I'm 2 days fresh out of the hospital on Lupron again. I pray this time I have a different outcome."

9 / 10
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More FAQ

  • 9 y...
  • Taken for 6 months to 1 year
  • December 1, 2022

"Was diagnosed 9 years ago, PSA 29. Had prostate removed in 2013, then PSA went up again, so had 37 radiation treatments. PSA started to rise again and after 7 years went up to 8.4. Started Lupron February 2022. PSA dropped to 0.3, which is good. Unfortunately, side effects eliminated sex life and now very weak/fatigued, so makes any exercise difficult and painful. Feet and legs hurt a lot when a hot flash starts, which happens up to a few times per hour, 24/7. This wakes me up all night. I guess I shouldn't complain as it is probably keeping me alive. I get 3 or 4 month shots."

7 / 10
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  • Mik...
  • Taken for 1 to 2 years
  • November 9, 2024

For Prostate Cancer "Given all the things that testosterone regulates in the male body, none of the side effects are unexpected. My blood work indicates that it’s working. The hot flashes, weight gain, fatigue, and mild vertigo (among other side effects) subsided in a few months, just in time for the next every-four-month injection."

9 / 10
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  • any...
  • Taken for 2 to 5 years
  • December 2, 2024

For Prostate Cancer "I have been on Lupron for 20 months now, and it reduced my PSA from .64 to undetectable. The side effects for me have been hot flashes a couple of times a day, loss of body hair, 20 pounds of weight gain, and complete loss of my sexual function and appetite. I will be going off Lupron when this shot wears off in a couple of months. I have been receiving the 6-month shot. I am 67 years old and have high-risk prostate cancer, have had my prostate removed, and went through 38 rounds of radiation. I feel I am doing as well as can be expected and do everything I like to do minus my libido. Good luck to all!"

7 / 10
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  • Bil...
  • Taken for 6 months to 1 year
  • November 30, 2024

For Prostate Cancer "I was diagnosed with high-risk prostate cancer. I opted for complete removal of the prostate and follow-up treatment of ADT and radiation treatment. My first injection was June 2023, and the second was January 2024. PSA test every three months since the first injection, and PSA was 0.00. I experienced many of the normal side effects from the Lupron injections, the worst has been the fatigue, joint pain, sweats, and hot flashes. It has been almost a year since my last injection. I still have some lingering side effects, with the worst and most often the sweats and hot flashes."

8 / 10
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  • Tom...
  • June 16, 2016

For Prostate Cancer "Been on this drug for 15 months. No libido at all, day sweats, night sweats, and hot flashes, irritability, and erratic memory episodes. PSA from 30 to 0.01 after radiation and continues today."

5 / 10
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  • Bil...
  • Taken for 1 to 6 months
  • October 28, 2024

For Prostate Cancer "Hot flashes, heavy sweating. These happen all times of day and night. I am in the 3rd month of a 6-month injection. I don't yet know about the results."

9 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • October 25, 2024

"Dosage: 3-month interval injection. Duration of treatment: 6 months. Results: bleeding stopped completely in the fourth (4) month after the first injection. Side effects: hot flashes, acne so far."

8 / 10
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