Lupron and Depression: What Users Say

• klu...
• Taken for 6 months to 1 year
• July 26, 2017

For Prostate Cancer "I was diagnosed in September 2016 with prostate cancer, and I have been on Lupron ever since. In between, I had 37 radiotherapy sessions. I have to be on Lupron for 2 years, but I would love to end it now. It has done okay at lowering PSA, but my QOL has suffered greatly, along with that of my dear wife. My mental health has taken a big hit with extreme depression and anxiety, and bodily I have no strength and no ED. It works great for some men without any side effects, but for others like me, they can be overwhelming. Best wishes to all on this journey. Kluff."

• Mrs...
• Taken for 1 to 6 months
• November 3, 2013

For Endometriosis "I was given the three-month injection in July 2012, with no mention of the potential side effects. I have been off Lupron for over one year and still have debilitating bone, joint, and muscle pain. I have had significant hair loss, short-term memory problems, and depression. My physical disabilities mean I will probably have to give up work. It is disgraceful that this drug was given to me with no discussion around these life-changing side effects. I'm worse now than before I started!!"

• Jus...
• Taken for 6 months to 1 year
• May 10, 2017

For Endometriosis "Many years of pain - After exploratory surgery and a part of one ovary taken, then laparoscopic 3 times to get rid of the endo, I thought this was going to be my saving grace! It has ruined my life, and I'm talking well over 20 years ago. If I remember correctly, it was a new drug they were trying at the time. Yes, it stopped my period and pain, but literally jumped from 110 to 140 in one month, had a complete breakdown, first time ever in my life breaking a glass table. Depression and anxiety and anger became my life. I reported all symptoms, even the little ones, such as sweating and not sleeping, hot flashes, etc. So not worth the lasting side effects, depression never went away! Don't use this drug, it took my happiness in life -"

• cak...
• March 2, 2016

For Endometriosis "I was diagnosed with endometriosis and polycystic ovaries when I was just 16 years old. I'm now 22, and I've gone through 9 birth control pills and 9 different gynos. I had a laparoscopic surgery when I was 17, which removed scar tissue and large cysts from my ovaries. After the surgery, I was on birth control (Seasonique, which is wonderful for endometriosis), and up until a year ago, I hadn't had many issues with pain. I started to get the pains again, along with bleeding for 3 months on birth control, so I went ahead with Lupron. After reading up on it, I was hesitant but moved forward. It stopped the bleeding, but the pain is still there, and now my joints ache every day, and also depression and suicidal thoughts are always there. Do not do it."

• Car...
• Taken for 1 to 2 years
• October 15, 2024

For Prostate Cancer "I have been on Lupron for 16 (of scheduled 18 months) to help suppress the return of prostate cancer. So far, the cancer is resolved. The side effects for me have been tiredness, mild depression, leg weakness and mild leg pain, mental fog, weakened memory, diminished thought clarity, significant muscle reduction, and lack of energy. Also, occasional diarrhea. Use was probably effective as cancer has not returned."

• Ann...
• September 10, 2014

For Endometriosis "Third shot of Lupron and suffering a lot. Joint pain and depression. But the doctor does not agree it has side effects."