Lupron and Headaches: What Users Say

• alb...
• Taken for 1 to 6 months
• May 7, 2016

For Prostate Cancer "This is pure poison. I have very bad side effects from this poison, and the doctor said he can do nothing. The physical and mental pain is so bad: hot flashes, very high blood pressure, headaches every day, pain urinating, joint pain, mental confusion, brain fog, memory loss, totally itchy all over, sleeplessness, very bad fatigue, and a lot more. My doctor never told me anything about this poison, just injected me with a 6-month supply at $6,000.00."

• Anonymous
• February 18, 2012

For Endometriosis "I have been on the Lupron shot now for 5 months. I have had no periods or period-associated pain since the second month. There is some minor pain and irritation at the injection site for a day or two after the shot. I have had pretty intense hot flashes and night sweats, minor joint and muscle pain, but the worst for me has been the massive headaches. I am taking another medication now to help with those. I would still recommend the shot if your endometriosis is severe, the side effects still aren't as bad as the pain I was in before. Trying to hang in there for another 4 months."

• kf7...
• Taken for 1 to 2 years
• July 20, 2012

For Endometriosis "I was on Lupron twice for endometriosis. The first time I had hot flashes and headaches, after I got off, they went away. The second time I had the same side effects, except when I got off of Lupron, the headaches did not go away and turned into migraines. Now I have had migraines for 16 years since being off of Lupron. I was never plagued with headaches before Lupron. My doctor said I always had the trigger for migraines and Lupron flipped the switch on. If I knew then what I know now, I would have taken a different approach to treating my endometriosis. Having endometriosis and migraines together was worse. Now I'm in menopause and going through everything to the nth degree."

• Anonymous
• October 3, 2011

For Endometriosis "I started the Lupron at the beginning of the summer, April 2011, to be exact. The only side effect I can say I had trouble with was the hot flashes, but nothing unbearable and usually over pretty quick. The first 3-4 weeks after an injection, I would have issues with vaginal dryness, but again, nothing unbearable. I had no mood swings or crazy headaches, but I have been constantly plagued with headaches since I was a child, so I wouldn't know if this had any effect on those. Overall, it has been a totally bearable experience, and the hot flashes were nothing compared to the pain I had before the Lupron. I would suggest it if your endometriosis is bad enough."

• Fut...
• April 17, 2013

For Endometriosis "I was diagnosed with fibroids twice, an ovarian cyst 8 cm big, and endometriosis. I'm going to take my third dose in two weeks, and I was prescribed this medicine for six months. Pros: after the first injection, no periods! Five months without a period was right up my alley, being I had been bleeding so much for so long, I needed the break. Cons: if you eat salty food or heavy carbs, you feel like you are going to throw up. Hot and cold flashes, sweats, stiff joints, joint pain, headaches, sleeplessness/severe insomnia, dry skin and dry eyes. I could go on, but I'm doing this to rid myself of ongoing bleeding, pain, and infertility. It's worth it to stick it out if it really works, I don't know if it does yet, but I know I'm not bleeding."

• Mau...
• Taken for 1 to 6 months
• August 19, 2015

For Endometriosis "I've received my first round in June 2015. Almost immediately, I started experiencing side effects. Headaches, weight gain, hot flashes, constant sweating, mood swings, made my depression worse, now swollen legs and ankles, also severe joint pain. This is becoming unbearable, and I'm rethinking doing the next cycle. It's helped with my endometriosis, which I'm happy about, but these side effects are a...."

• Lan...
• December 28, 2016

For Uterine Fibroids "I am on a 3-month shot plan but monthly shots. I didn't want the 3-month all at once because I wanted to see how my body would react to it first. Shot given 12/07/16, and today is 12/28/16. The first week, I didn't really have any side effects, and I was really hopeful that this would be the worst. Wishful thinking didn't last long. Hot flashes, night sweats, chills, emotional wreck, and I believe slight headaches that come and go. BUT, on the contrary, less than a month and my fibroid has already physically shrank. I haven't seen the doc yet, but I can physically see that it shrank. My clothes are loose in the belt line area. My fibroid was the size of a small grapefruit (17 cm), but I really see a huge difference in shrinkage. Could be worse :/"

• Anonymous
• Taken for 1 to 6 months
• November 24, 2015

For Uterine Fibroids "Received a 3-month injection 8/20 for heavy bleeding due to fibroids. Did not stop bleeding/spotting until the middle of October. Now I need another dose, and the price jumped from $10 (promo fee) to $1,100-$3,000. Needless to say, I cannot afford the next round. Also had a headache for the full 3 months. However, my doctor said it did shrink my fibroid enough to get the ablation I need."

• San...
• Taken for less than 1 month
• October 2, 2012

For Female Infertility "Extreme headaches! Lupron - I started the medication 5 days ago, and starting on day 3, I began getting really bad headaches, and it doesn't seem to ever go away. I cannot take Advil, so I'm not sure if that would help. I tried taking a nap, but I wake up, and it's still there. Never had this problem before, so I'm certain it's the Lupron. Other than that, I have no other complaints."