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Itraconazole and Tiredness: What Users Say

Brand names: Sporanox, Tolsura

Tiredness: mentioned by 9 users (17.0%)

Based on user experiences from 53 Itraconazole reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

tiredness 17.0%
headaches 9.4%
anxiety 7.5%

Reviews for Itraconazole

Commonly mentioned side effects
  • Bog...
  • June 27, 2009

Itraconazole for Onychomycosis, Toenail "One small nail had 100% infection while 2-3 other toes (including big toes) were slightly affected. After one month it was clear. Sporanox was very effective. Healthy nail growth was apparent. But I stopped using the medicine because of the side effects, namely the sense of abnormal heart and mental function (not unlike the effects of pseudoephedrine), together with headaches and tiredness. I tried Lamisil for one month, and the improvement continued, but I suffered from nausea, tiredness, and occasional headaches. Now I have just started Diflucan."

5 / 10
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46 Report
  • Anonymous
  • Taken for less than 1 month
  • July 23, 2020

Itraconazole for Onychomycosis, Toenail "I was prescribed Sporanox to take as a pulse therapy for a toenail fungal infection. Day 1 was okay. Woke up at night, thirsty and with a feeling of sand in my mouth. Day 2, small cough and breathing not 100%. Day 3, the worst nightmare of my life. Let me just say, I'm a healthy young person, running around 80 miles a month in addition to regular gym sessions. My resting HR is 45. Never in my life have I had even a headache. That day, I was extremely tired, coughing, the strongest headache in my life, constantly thirsty, literally thought the next stage was dying. It's day 5 (I stopped on day 3), and I still feel a headache and the lymph nodes behind my ears hurt very much for the second day in a row. I can't move my head too much without hurting. If you're thinking of taking this for a fungal infection in toes or fingers, consider a different therapy like laser options. It was too short of a therapy to see any effects, so I can't say if it would be effective, the side effects were too much."

1 / 10
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22 Report
  • Joh...
  • Taken for less than 1 month
  • April 22, 2018

For Dermatophytosis "I've been on this for 6 days, 100 mg per day, cleared my fungal infection on feet, but side effects were sore throat, runny nose, cold symptoms, feeling tired, joint pain, and mild abdominal pain. You should take this after a full meal."

7 / 10
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12 Report

Frequently asked questions

  • Bir...
  • Taken for less than 1 month
  • May 7, 2021

For Blastomycosis "I started a high dose. Had to stop as my liver and kidney levels went high. Then a couple of weeks later, started me again on 1 dose twice a day. Day 3, feeling sick, headaches, numbness, tingling in hands, tired, just not myself at all. I just sent another message to my doctor to see what to do. Also, I keep feeling like my heart is racing. I’m not liking it. That is, my body is not liking it."

1 / 10
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6 Report
  • Anonymous
  • October 18, 2016

For Histoplasmosis "Itraconazole literally saved my life. I had a life-threatening case of pulmonary histoplasmosis disseminating to my liver. Thankfully, my infectious disease doctor caught it in time and started me on a pulsating dose of itraconazole while in the hospital. I stayed on a maintenance dose of 100 mg for two years and just now got off. I had zero side effects other than being a bit tired, but it was worth it. I highly recommend this drug for histo patients."

10 / 10
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14 Report

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  • Ren...
  • Taken for 6 months to 1 year
  • December 28, 2021

For Blastomycosis "I have been taking it for 6 months. I was very ill when I first started. I almost died. I have to take it for at least one year. The side effects are not fun, my hair is falling out, my neuropathy has gotten extremely worse, my hands get very blue and loose feeling, my balance is being affected, I am very tired, my joints are very painful, and my eyesight has been affected. With all that said, if it is helping get the Blastomycosis out of my system, keeping me out of the hospital, not on a ventilator, I guess I am willing to put up with the multitude of side effects. I take the liquid form, 20 mg two times a day. So far, the scans of my lungs have shown much improvement. I just hope that the side effects will diminish when I stop taking the drug."

10 / 10
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  • BTa...
  • Taken for less than 1 month
  • July 2, 2016

"I'm suffering from Tinea Cruris for over 3 months now. Tried different remedies. None of them worked. Tried topical creams such as Clotrimazole, Dactarin, and Lamisil. None of them brought any relief. After consultation with my GP, I took a liver function blood test, and when the results came back satisfactory, I was prescribed 200 mg of Sporanox/Itraconazole for 1 week. No effect was noticed during the drug course, although after a few days, the fungus started to disappear from my penis head. A week later, everything came back with a 'double kick', the rash from my groin did not go at all. Everything is the same. Side effects: After the course, I felt very tired and nervous, but this went away after a couple of days. Now I have to look for some other solution!!!"

2 / 10
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8 Report
  • Mix...
  • Taken for 1 to 6 months
  • October 4, 2021

For Tinea Capitis "I was prescribed this medication for tinea corporis, and I was taking another brand for 2 months, and it wasn’t working too well. The fungal infection was controlled but not improving or going away, after which the doctor prescribed me the same medication from a different brand, but this time a lesser dosage, and it worked like a charm. But it brought along a lot of side effects - excessive sweating, tiredness, disturbed sleep (can only sleep 4 hours a day), and the WORST side effect (for women) my periods completely stopped, and because of which my hormones went out of whack, and I got insane cystic hormonal acne, which I have never had in my life. Nor have I ever missed a period. I just can’t wait to get it done with because I’m so tired of waking up to 3/4 pimples every single day."

5 / 10
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  • Jjg...
  • July 4, 2015

For Histoplasmosis "Skin felt burning hot the first 3 days & very tired."

8 / 10
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6 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.