Skip to main content

Itraconazole and Headaches: What Users Say

Brand names: Sporanox, Tolsura

Headaches: mentioned by 5 users (9.4%)

Based on user experiences from 53 Itraconazole reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

tiredness 17.0%
headaches 9.4%
anxiety 7.5%

Reviews for Itraconazole

Commonly mentioned side effects
  • Bog...
  • June 27, 2009

Itraconazole for Onychomycosis, Toenail "One small nail had 100% infection while 2-3 other toes (including big toes) were slightly affected. After one month it was clear. Sporanox was very effective. Healthy nail growth was apparent. But I stopped using the medicine because of the side effects, namely the sense of abnormal heart and mental function (not unlike the effects of pseudoephedrine), together with headaches and tiredness. I tried Lamisil for one month, and the improvement continued, but I suffered from nausea, tiredness, and occasional headaches. Now I have just started Diflucan."

5 / 10
Was this helpful?YesNo
46 Report
  • Bog...
  • June 27, 2009

Itraconazole for Onychomycosis, Toenail "One small nail had 100% infection while 2-3 other toes (including big toes) were slightly affected. After one month it was clear. Sporanox was very effective. Healthy nail growth was apparent. But I stopped using the medicine because of the side effects, namely the sense of abnormal heart and mental function (not unlike the effects of pseudoephedrine), together with headaches and tiredness. I tried Lamisil for one month, and the improvement continued, but I suffered from nausea, tiredness, and occasional headaches. Now I have just started Diflucan."

5 / 10
Was this helpful?YesNo
46 Report
  • Anonymous
  • Taken for less than 1 month
  • July 23, 2020

Itraconazole for Onychomycosis, Toenail "I was prescribed Sporanox to take as a pulse therapy for a toenail fungal infection. Day 1 was okay. Woke up at night, thirsty and with a feeling of sand in my mouth. Day 2, small cough and breathing not 100%. Day 3, the worst nightmare of my life. Let me just say, I'm a healthy young person, running around 80 miles a month in addition to regular gym sessions. My resting HR is 45. Never in my life have I had even a headache. That day, I was extremely tired, coughing, the strongest headache in my life, constantly thirsty, literally thought the next stage was dying. It's day 5 (I stopped on day 3), and I still feel a headache and the lymph nodes behind my ears hurt very much for the second day in a row. I can't move my head too much without hurting. If you're thinking of taking this for a fungal infection in toes or fingers, consider a different therapy like laser options. It was too short of a therapy to see any effects, so I can't say if it would be effective, the side effects were too much."

1 / 10
Was this helpful?YesNo
22 Report

Frequently asked questions

  • Bir...
  • Taken for less than 1 month
  • May 7, 2021

For Blastomycosis "I started a high dose. Had to stop as my liver and kidney levels went high. Then a couple of weeks later, started me again on 1 dose twice a day. Day 3, feeling sick, headaches, numbness, tingling in hands, tired, just not myself at all. I just sent another message to my doctor to see what to do. Also, I keep feeling like my heart is racing. I’m not liking it. That is, my body is not liking it."

1 / 10
Was this helpful?YesNo
6 Report
  • Ary...
  • Taken for less than 1 month
  • January 30, 2022

For Dermatophytosis "Started a course of 50 mg twice a day itraconazole, developed a mild to moderate headache every time I had a dose. Drinking a lot of water and having some food helped in reducing the headaches. However, a mild headache persisted throughout the day. I stopped taking the medicine after 5 days due to the headache, and now I am relying on a topical antifungal agent for a yeast infection. Did not have any other side effects, however, headache persisted throughout the day."

5 / 10
Was this helpful?YesNo
1 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.