Skip to main content

Immune globulin subcutaneous and Headaches: What Users Say

Brand names: Hizentra, Xembify, Cuvitru, Cutaquig

Headaches: mentioned by 4 users (7.7%)

Based on user experiences from 52 Immune globulin subcutaneous reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

swelling 9.6%
headaches 7.7%
bumps 5.8%
nausea 5.8%
rash 5.8%

Reviews for Immune globulin subcutaneous

Commonly mentioned side effects
  • She...
  • Taken for 6 months to 1 year
  • December 28, 2018

For Primary Immunodeficiency Syndrome "First put on Hizentra. That worked like a miracle. That is, until my gradual itchiness turned into full hives after one infusion. So that was stopped. Cuvitru was next prescribed. As a nurse friend noted, often it's the 'stabilizer' that people are allergic to. I still have lightly raised hives, but they aren't full on or totally itchy. More like dry skin. Other reactions are redness at the infusion site for about 12 hours... gone the next day. Sometimes exhaustion that literally can knock me out for anything up to 2 hours in the mid-afternoon. Slight feeling in my head of cold and headache. Again, you can prep with Tylenol (I do not) and Benadryl. (I do not, since it does put me to sleep). The medication has kept me healthy. I no longer sweat being around children or adults who are coughing. The weekly infusion does run my life on that day, but the trade-off to be healthy and not sick on antibiotics 4 plus times a year (often with second rounds) makes the trade-off worth my while."

9 / 10
Was this helpful?YesNo
38 Report
  • Aug...
  • Taken for less than 1 month
  • March 30, 2018

For Primary Immunodeficiency Syndrome "I just had my third subcutaneous infusion of Hizentra. I have had a few side effects, such as itching at injection sites only on the first infusion. Today, I had a small headache and heartburn. I was easily able to treat this with OTC meds. But the good news is I am able to do things I love for the first time in 15 years. Don’t wait to get this med started. I hope you will be a success story too!"

10 / 10
Was this helpful?YesNo
36 Report
  • Clo...
  • Taken for 6 months to 1 year
  • August 11, 2017

For Primary Immunodeficiency Syndrome "I was on Hizentra and never felt well - ever! During infusion, I would immediately become nauseated. Shortly thereafter, I would experience a horrible headache. My pre-medications were Zofran, Zomig (for my migraine problems), Tylenol, and Benadryl. My trough level was at a decent level, so I was able to have my sinus surgery. I had post-sinus infections of 3 different bacteria. I just kept getting sicker and sicker. Hizentra was the worst drug interactions ever put into my body for 8 months!"

2 / 10
Was this helpful?YesNo
18 Report
  • gab...
  • Taken for 1 to 6 months
  • June 3, 2023

For Primary Immunodeficiency Syndrome "I've had Hizentra on and off for 4 months. Every time I start the treatment with only 2 grams, when I got to 4 grams, the symptoms were terrible: nausea, lack of appetite, high blood pressure, debilitating headaches, etc. The worst part was being told by my doctor that these symptoms could not happen with Hizentra and now reading all your reviews! Thank you for sharing!"

3 / 10
Was this helpful?YesNo
3 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.