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Hizentra and Swelling: What Users Say

Swelling: mentioned by 4 users (12.5%)

Based on user experiences from 32 Hizentra reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

swelling 12.5%
headaches 9.4%
nausea 9.4%
pain 9.4%

Reviews for Hizentra

Commonly mentioned side effects
  • Can...
  • Taken for 2 to 5 years
  • November 22, 2020

For Primary Immunodeficiency Syndrome "I am 62, have been on Hizentra infusions for 2 years, and do the infusions in my stomach. Over the last year, my stomach has gotten really puffy and bloated. I called the Hizentra pharmacy, and they told me that was a side effect to change infusion sites. I will do that and let you know what happens."

8 / 10
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21 Report
  • Bug...
  • October 21, 2015

For Primary Immunodeficiency Syndrome "I have had 6 treatments. My goal is not to have bronchitis, sinusitis, or pneumonia repeatedly. For 48-72 hours post-rx, my abdomen is hot pink, swollen, and painful. I then feel fantastic for 6 days, and then my malaise gradually kicks back in. I had a 3-month 'virus' at age 11. I was unable to walk for more than a few feet at a time. I have never felt good since. Life was not what it should have been. My 'awesome' days are well worth all the downsides of this rx. The only regret is that I could have had it sooner. I am so thankful for this medication."

7 / 10
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31 Report
  • Rum...
  • Taken for 1 to 6 months
  • September 28, 2020

For Primary Immunodeficiency Syndrome "I just had my second Hizentra treatment of 6 injections, but this time in my arm. It has been about 8 hours since my treatment ended, and I have been in bed pretty much since then. My arm at the injection sites is hot and swollen, which I can deal with. I did better on gamma globulin despite having lousy veins. My sinus and ear infection symptoms returned mid-treatment. Not sure I will continue since I am feeling ill and vaguely drugged. I just had a kitchen accident and yelled at my hungry cats for jumping around."

2 / 10
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8 Report
  • sab...
  • Taken for less than 1 month
  • June 24, 2025

For Chronic Inflammatory Demyelinating Polyradiculoneuropathy "6/23/25 first infusion was not hard to do. started late afternoon waiting for a nurse teacher. 3:30. Finished at 7:30. Took a lot longer than I expected. Only one site was painful (had three). The other two were non-feeling. After removing the needles, the left side of my stomach was still painful. My upper stomach is very swollen, hard, and extremely tender. It is very, very red. I'm not at all sure about this medication."

5 / 10
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0 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.